化痰解郁安神汤联合中医情志疗法治疗失眠伴抑郁症的临床研究  

Clinical Efficacy of Huatan Jieyu Anshen Decoction(化痰解郁安神汤)Combined with TCM Emotional Therapy on Insomnia with Depression

作　　者：蔡铁如[1] 伍大华[2] CAI Tie-ru WU Da-hua(Hu＇nan Academy of Chinese Medicine, Changsha Hu＇nan 410006, China The Affiliated Hospital of Hu＇nan Academy of Chinese Medicine, Changsha Hu＇nan 410006, China)

机构地区：[1]湖南省中医药研究院,湖南长沙410006 [2]湖南省中医药研究院附属医院,湖南长沙410006

出　　处：《中医药导报》2017年第13期101-104,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：湖南省中医药科研计划项目(编号:201125)

摘　　要：目的:观察化痰解郁安神汤联合中医情志疗法治疗失眠伴抑郁症的临床疗效。方法:将60例失眠伴抑郁症患者随机分为治疗组和对照组各30例,对照组予西医常规治疗,治疗组采用化痰解郁安神汤联合中医情志疗法治疗。比较两组匹茨堡睡眠质量指数量表(PSQI)评分、汉密尔顿抑郁量表(HAMD)评分、中医证候疗效、综合疗效与远期复发率。结果:两组PSQI、HAMD评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05);中医证候疗效与综合疗效总有效率治疗组分别为96.4%、92.9%,对照组均为70.4%,组间比较,差异均有统计学意义(P<0.05);随访3个月后复发率治疗组为15.0%,对照组为36.4%,组间比较,差异有统计学意义(P<0.01)。结论:化痰解郁安神汤联合中医情志疗法治疗失眠伴抑郁症患者疗效明显优于西医常规疗法治疗。Objective： To observe the clinical efficacy of Huatan Jieyu Anshen decoction combined with tra- ditional Chinese medicine （TCM） emotional therapy in the treatment of insomnia with depression. Methods： The 60 insomnia patients with depression were randomly divided into control and treatment groups, 30 cases in each. The patients received conventional Western medicine therapy in control group, and Huatan Jieyu Anshen decoc- tion combined with TCM emotional therapy in treatment group. The Pittsburgh Sleep Quality Index （PSQI） score, Hamilton Depression Scale （HAMD） score, TCM syndrome outcome, overall treatment outcome, and long-term re- currence rate were compared between the two groups. Results： After treatment, both groups showed significant changes in PSQI and HAMD scores （P〈0.05）, and there were significant differences in PSQI and HAMD scores between the two groups （P〈0.05）. The overall response rates for TCM syndrome outcome and overall treatment outcome were 96.4% and 92.9% in treatment group respectively, and 70.4% in control group. The treatment group showed higher overall response rates than the control group （i~〈0.05）. The 3-month follow-up showed that the recurrence rate was 15.0% in treatment group and 36.4% in control group; the treatment group showed low- er recurrence rate thanthe control group （P〈0.01）. Conclusion： Huatan Jieyu Anshen decoction combined with TCM emotional therapy is more effective than conventional Western medicine therapy in the treatment of insom- nia with depression and holds promise for clinical application.

关 键 词：失眠症 抑郁症 化痰解郁安神汤 情志疗法 

分 类 号：R255[医药卫生—中医内科学]