处理后前向运动精子总数对夫精宫腔内人工授精结局的影响  

Influence of total progressively motile sperm count after treatment on outcomes of intrauterine insemination with husband's sperm

作　　者：朱娟[1,2] 黄元华[1] 卢伟英[1] 张毅[1] 黄炜[1] 毛记龙[1] 马燕琳[1,2] 羊在家[3] 

机构地区：[1]海南医学院第一附属医院生殖中心,海口570102 [2]南方医科大学,广州510515 [3]海南医学院管理学院,海口571199

出　　处：《重庆医学》2017年第20期2758-2760,共3页Chongqing medicine

基　　金：国家自然科学基金资助项目(81460034);海南省重大科技项目(ZDZX2013003);海南省哲学社会科学规划课题(HNSK[QN]15-23)

摘　　要：目的研究处理后前向运动精子总数(TPMSC)对促排卵周期夫精宫腔内人工授精(IUI)的临床结局的影响。方法回顾性分析行促排卵周期IUI治疗的4 179例患者的临床资料,分析临床妊娠率与处理后TPMSC的关系。结果所有患者的临床资料中TPMSC偶见活精至100×10~6。TPMSC<0.15×10~6有15例,有1例妊娠(IUI日精液处理后偶见活精);TPMSC>60×10~6有10例,均未妊娠。对TPMSC(0.15~60.00)×10~6的共4 154例病例进行分析。各组女性年龄、不孕年限、卵泡数、子宫内膜厚度的比较差异无统计学意义(P>0.05)。临床妊娠率为13.5%(576/4 154),最高的组为(5.00~<10.00)×10~6(16.0%),各组的临床妊娠率比较差异无统计学意义(P=0.133)。结论处理后TPMSC在(0.15~60.00)×10~6行IUI均可达到较好的妊娠率。Objective To investigate the influence of total progressively motile sperm count（TPMSC） after treatment on clinical outcomes of intrauterine insemination（IUI） with the husbandrs sperm in ovulation-promoting cycles. Methods The clinical data in 4179 cases undergoing IUI with the husbandrs sperm in ovulation-promoting cycles were retrospectively analyzed. The corre- lation between clinical pregnancy rate and TPMSC was analyzed. Results Among all the clinical data,TPMSC was to 100 × 106 in occasional live sperm. TPMSC〈0.15 × 106 was in 15 cases, 1 case had pregnancy （live sperm was occasionally seen on IUI day after sperm processing）. Ten cases of TPMSC 〉60 × 106 had no pregnancy. A total of 4 154 cases of TPMSC （0.15- 60.00） × 106 were analyzed. The female age,duration of infertility,number of follicles and endometrial thickness（EDM） had no statistical differences among various groups. The clinical pregnancy rate was 13.5 % （576/4 154） ,the group with the highest clinical pregnancy rate was （5.00-10.00） × 106. But there was no statistically significant difference in clinical pregnancy rate among groups（P= 0. 133）. Conclusion Performing IUI in PMSC （0.15- 60.00） × 106 after processing can get preferable pregnancy rates.

关 键 词：宫腔内人工授精 妊娠率 前向运动精子总数 

分 类 号：R714.8[医药卫生—妇产科学]