喉癌术后患者医院感染病原菌分布及耐药性分析  

Analysis on the pathogen distribution and drug resisitance of hospital infection in postoperative patients with laryngeal carcinoma

作　　者：毛晓春[1] 毛剑锋[2] 楚旭[2] 

机构地区：[1]浙江省肿瘤医院,浙江杭州310022 [2]浙江萧山医院

出　　处：《中国消毒学杂志》2017年第6期548-550,共3页Chinese Journal of Disinfection

摘　　要：目的了解喉癌术后患者医院感染病原菌的临床分离和耐药情况,为临床合理用药及感染控制提供依据。方法通过回顾性调查方法,对某医院住院喉癌手术患者术后医院感染病原菌分离和药敏试验结果进行调查和分析。结果共调查683例喉癌手术患者,发现医院感染88例,感染发生率为12.9%。在感染患者中,肺部感染居首位,构成比占53.4%,主要病原菌为肺炎克雷伯菌,其中产超广谱β-内酰胺酶(ESBLs)菌株占29.03%。其次是手术切口感染,构成比占28.4%,主要病原菌为金黄色葡萄球菌,其中甲氧西林耐药金黄色葡萄球菌(MRSA)菌株占31.25%。结论喉癌术后患者医院感染以肺部和手术切口感染为主,常见病原菌为肺炎克雷伯菌和金黄色葡萄球菌,应有针对性地建立防控措施。Objective To investigate the clinical isolation and drug resistance of pathogens isolated from patients with laryngeal carcinoma after surgery,provide evidence for clinical rational drug using and infection control. Methods Retrospective investigation was used to analyze the clinical data of pathogenic bacteria distribution and drug resistance of patients with laryngeal carcinoma in our hospital. Results 88 cases had hospital infection in total of 683 patients with laryngeal carcinoma after surgery. The infection rate was 12. 9%. Most of them presented with pneumonia（ 53. 4%） and the main bacteria was Klebsiella pneumonia,of them extended-spectrum β-lactamases（ ESBLs） Klebsiella pneumonia accounted for29. 03%. The second was wound infection（ 28. 4%） and the main bacteria was Staphylococcus aureus,of them Methicillin resistant Staphylococcus aureus（ MRSA） accounted for 31. 25%. Conclusion Hospital infection in patients with laryngeal carcinoma is mainly caused by lung and wound infection,and the common pathogens are Klebsiella pneumonia and Staphylococcus aureus. We should strengthen the management of control and prevention.

关 键 词：喉癌手术患者 医院感染 病原菌 耐药性 

分 类 号：R378[医药卫生—病原生物学]