针刺促进脊髓损伤后神经功能恢复的机制及相关信号通路的作用  

Mechanism of Acupuncture for Recovery of Neurological Function after Spinal Cord Injury and Role of Related Signal Pathway(review)

作　　者：李华南[1] 张海明[1] 顾兵[2] 原琴琴 闵友江[1] 

机构地区：[1]江西中医药大学附属医院创伤骨科,江西南昌市330006 [2]江西科技师范大学药学院,江西南昌市330013

出　　处：《中国康复理论与实践》2017年第6期641-644,共4页Chinese Journal of Rehabilitation Theory and Practice

基　　金：国家自然科学基金项目(No.30960448;No.81360562);江西省自然科学基金项目(No.20142BAB205023)

摘　　要：本文介绍针刺促进脊髓损伤后神经功能恢复的主要生物学机制,包括抑制炎症反应和氧化应激,减轻神经病理性疼痛,增加神经营养活性物质,调节细胞生存/凋亡基因和神经再生信号通路。This article introduced the main biological mechanisms of acupuncture promoting nerve function recovery after spinal cord injury, which include inhibition of inflammation and oxidative stress, alleviation of neuropathic pain, increase of neurotrophic active substance, regulation of cell survival/apoptosis gene and neural regeneration pathway.

关 键 词：脊髓损伤 针刺 神经功能 氧化应激 神经病理性疼痛 凋亡 信号通路 综述 

分 类 号：R651.2[医药卫生—外科学]