医院感染对急性心肌梗死患者生存质量及体液免疫状态的影响研究  

Influence of nosocomial infections on quality of life and humoral immunity state of patients with acute myocardial infarction

作　　者：赵晓燕[1] 宋雅信 Galimkhan Nurjanar 丁红炀 姚连涛[1] 胡洋洋[1] 

机构地区：[1]郑州大学第一附属医院心血管内科,河南郑州450052

出　　处：《中华医院感染学杂志》2017年第13期2954-2956,2983,共4页Chinese Journal of Nosocomiology

基　　金：河南省高等学校重点科研基金资助项目(16A320029)

摘　　要：目的研究医院感染对急性心肌梗死患者生存质量及体液免疫状态的影响,以进一步了解医院感染对急性心肌梗死患者的不良影响。方法选取2014年4月-2016年7月期间的70例急性心肌梗死并发医院感染患者为A组,70例心肌梗死无医院感染患者为B组,70名体检健康同龄者为C组,将三组研究对象的生存质量及体液免疫指标进行评估、检测及比较,并比较A组中不同感染部位患者的评估与检测结果。结果 A组的世界卫生组织生存质量测定量表简表(WHOQOL-BREF量表)心理状态、生理状态、环境领域及社会关系评分分别为(49.20±4.84)分、(41.35±4.66)分、(44.98±3.67)分及(39.88±4.20)分,均低于B组的(59.17±5.23)分、(50.21±5.32)分、(53.63±4.41)分、(51.35±5.26)分及C组的(72.53±5.73)分、(73.63±6.18)分、(68.46±4.97)分、(78.56±6.43)分,B组评分则低于C组,同时A组的体液免疫指标均低于B组及C组,B组则低于C组(P<0.05),而A组中不同感染部位患者的生存质量评分及体液免疫指标则无明显差异。结论医院感染对急性心肌梗死患者生存质量及体液免疫状态的不良影响较为突出,因此认为对于急性心肌梗死患者尤其应重视医院感染的防控与诊治。OBJECTIVE To study the influence of nosocomial infections on quality of life and humoral immunity state of patients with acute myocardial infarction so as to further understand the adverse effect of nosocomial infections on the patients with acute myocardial infarction.METHODS A total of 70 acute myocardial infarction patients complicated with nosocomial infections who were treated in the hospital from Apr 2014 to Jul 2016 were chosen as the group A,70 myocardial infarction patients without nosocomial infection were chosen as the group B,and 70 healthy people who received physical examination were set as the group C.The quality of life and humoral immunity indexes were assessed,detected,and compared among the three groups of study objects,and the assessment and detection results were compared among the patients with different sites of infections in the group A.RESULTS According to the World Health Organization Quality of Life Measurement Scale（WHOQOL-BREF scale）,the psychological state score of the group A was（49.20±4.84）points,lower than（59.17±5.23）points of the group B and（72.53±5.73）points of the group C;the physiological state score of the group A was（41.35±4.66）points,lower than（50.21±5.32）points of the group B and（73.63±6.18）points of the group C;the environmental domain score of the group A was（44.98±3.67）points,lower than（53.63±4.41）points of the group B and（68.46±4.97）points of the group C;the social relationship score of the group A was（39.88±4.20）points,lower than（51.35±5.26）points of the group B and（78.56±6.43）points of the group C;the levels of humoral immunity indexes of the group A were lower than those of the group B and the group C,however,there was no significant difference in the score of quality of life or the humoral immunity indexes among the patients with different sites of infections in the group A.CONCLUSIONThe nosocomial infection has significant adverse impact on the quality of life and humoral immunity state of the patient

关 键 词：医院感染 急性心肌梗死 生存质量 体液免疫状态 

分 类 号：R542.2[医药卫生—心血管疾病]