生殖道解脲脲原体和衣原体感染与不孕症的相关性分析  

Correlation between reproductive tract Ureaplasma urealyticum and Chlamydia infectionand infertility

作　　者：王婉萍 沈玲珑 张甦 孙翠翔[2] 叶旭萍[2] 

机构地区：[1]湖州市妇幼保健院妇产科,浙江湖州313002 [2]复旦大学附属妇产科医院妇科,上海黄浦200011

出　　处：《中华医院感染学杂志》2017年第13期3059-3061,3065,共4页Chinese Journal of Nosocomiology

基　　金：浙江省医药卫生一般研究计划基金资助项目(2014KYB254)

摘　　要：目的探讨女性生殖道解脲脲原体和沙眼衣原体与不孕症的相关性,为临床不孕症的诊治提供依据。方法选择2013年1月-2016年1月医院就诊的不孕症患者400例为不孕症组,将其中160例原发性不孕症患者列为原发性不孕症组;240继发性不孕症患者列为继发性不孕症组;选择同期进行孕前检查或健康体检400例育龄女性为对照组;检查并分析不孕症组和对照组患者生殖道解脲脲原体和沙眼衣原体的感染情况。结果不孕症组的解脲脲原体、衣原体及解脲脲原体+衣原体的感染率均明显高于对照组(P<0.05);在不孕症患者中,不同年龄组解脲脲原体、衣原体及解脲脲原体+衣原体的感染率不同,20~<30岁、30~<40岁和40~45岁组感染率比较差异有统计学意义(P<0.05),其中20~<30岁组感染率最高,40~45岁组解脲脲原体、衣原体及解脲脲原体+衣原体的感染率明显低于20~<30岁及30~<40岁组。结论不孕症患者生殖道解脲脲原体和沙眼衣原体的感染率明显升高,对于不孕症患者应该重视生殖道解脲脲原体和沙眼衣原体的检查。OBJECTIVE To explore the correlation between the reproductive tract Ureaplasma urealyticum and Chlamydia trachomatis infection and infertility so as to provide guidance for clinical treatment of infertility.METHODS A total of 400 infertility patients who were treated hospitals from Jan 2013 to Jan 2016 were assigned as the infertility group,and 160 patients who had primary infertility were chosen as the primary infertility group,and 240 patients who had secondary infertility were set as the secondary infertility group,meanwhile 400 women at childbearing age who received pre-pregnancy examination or physical examination were chosen as the control group.The prevalence of reproductive tract U.urealyticum and C.trachomatis infection was observed and compared between the infertility group and the control group.RESULTS The incidence rates of U.urealyticuminfection,C.trachomatisinfection,and U.urealyticumplus C.trachomatisinfection were significantly higher in the infertility group than in the control group（P〈0.05）.The incidence rates of U.urealyticuminfection,C.trachomatis infection,and U.urealyticumplus C.trachomatisinfection varied among the patients with infertility in different age groups,and there was significant difference in the infection rate among the 20-〈30age group,30-〈40age group,and 40-45 age group（P〈0.05）,the infection rate was the highest in the 20-〈30age group;the incidence rates of U.urealyticuminfection,C.trachomatis infection,and U.urealyticumplus C.trachomatis infection were rsignificantly lower in the 40-45 age group than in the 20-〈30 age group and the 30-〈40 age group.CONCLUSIONThe incidence rates of U.urealyticuminfection and C.trachomatis infection are significantly increased in the patients with infertility,and it is necessary to pay attention to the detection of U.urealyticumand C.trachomatis.

关 键 词：不孕症 生殖道感染 解脲脲原体 沙眼衣原体 

分 类 号：R374[医药卫生—病原生物学]