糖尿病肾病治疗临床试验的研究进展  

Research Progress of Clinical Trials for the Treatment of Diabetic Nephropathy

作　　者：许倬[1] 涂晓文[1] 曹海丽[1] XU Zhuo TU Xiao-wen CAO Hai-li(Department of Nephrology, the General Hospital of the PLA Rocket Force, Beijing 100088, China)

机构地区：[1]中国人民解放军火箭军总医院肾脏内科,北京市100088

出　　处：《中国全科医学》2017年第20期2535-2538,共4页Chinese General Practice

摘　　要：糖尿病肾病是糖尿病患者常见的并发症之一,严重危害公众健康。尽管肾素-血管紧张素(RAS)拮抗剂、降压、降糖等治疗能够延缓糖尿病肾病的进展速度,但目前尚缺乏针对其发病机制的有效治疗,部分患者仍会进展至终末期肾病(ESRD)。为了给糖尿病肾病患者的临床治疗提供更多选择,本文就近期发表的临床随机对照试验进行综述。Diabetic nephropathy（ DN） is one of the common complications of diabetes mellitus that threatens human health severely. Although existing interventions such as inhibition of the renin-angiotensin system（ RAS）, lowering hypertension and hyperglycemia have been shown to slow the progression of DN,no treatments are directed at its pathogenesis effectively. Some patients may still progress to end-stage renal disease（ ESRD） ultimately. In order to offer more clinical options for DN management,we summarized the recent findings demonstrated in randomized controlled clinical trials.

关 键 词：糖尿病肾病 临床试验 综述 

分 类 号：R587.23[医药卫生—内分泌]