影响增殖性糖尿病视网膜病变玻璃体切除术后视力改善的因素（英文）  

Factors predicting visual improvement post pars plana vitrectomy for proliferative diabetic retinopathy

作　　者：Evelyn Tai Li Min Goh Yihu Wan-Hazabbah Wan Hitam Haslina Mohd Ali Evelyn Tai Li Min Goh Yihui Wan-Hazabbah Wan Hitam Haslina Mohd Ali(Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia Department of Ophthalmology, Hospital Suhanah Bahiyah, Alor Star 05150, Kedah, Malaysia)

机构地区：[1]马来西亚理科大学,健康校园,医学科学学院眼科 [2]Sultanah Bahiyah医院眼科,马来西亚吉打州亚罗士打05150

出　　处：《国际眼科杂志》2017年第8期1404-1409,共6页International Eye Science

摘　　要：目的:分析影响增殖性糖尿病视网膜病变(PDR)玻璃体切除术后视力改善的因素。方法:回顾性分析。收集2014-01/2014-12在马来西亚吉打州,亚罗士打Sultanah Bahiyah医院收治的PDR行玻璃体切除术病例资料,包括1y内患者统计,基线视力(VA)和LogMAR术后最佳矫正视力。使用IBM SPSS Statistics Version 22.0进行数据分析。结果:共103例患者。平均年龄51.2y。在多变量分析中,每个0 logMAR基线VA的1 logMAR术前正偏差与0.859logMAR的术后改善相关(P<0.001)。同样,术前附着的黄斑与玻璃体切除术后的logMAR视力改善相关(b=0.374,P=0.003)。无虹膜新血管和无术后并发症与玻璃体切除术后改善的logMAR视力相关,分别为1.126(P=0.001)和0.377(P=0.005)。无长效眼内填充与玻璃体切除术后logMAR视力改善相关,为0.302(P=0.010)。结论:玻璃体切除术后与视力改善的相关因素是:术前视力较差,黄斑附着,无虹膜新生血管,无术后并发症和未使用长效眼内填充物。了解视力改善的因素将有助于玻璃体视网膜手术的决策。AIM： To identify factors predicting visual improvement post vitrectomy for sequelae of proliferative diabetic retinopathy （PDR）.METHODS： This was a retrospective analysis of pars plana vitrectomy indicated for sequelae of PDR from Jan.to Dec.2014 in Hospital Sultanah Bahiyah,Alor Star,Kedah,Malaysia.Data collected included patient demographics,baseline visual acuity （VA） and post-operative logMAR best corrected VA at 1y.Data analysis was performed with IBM SPSS Statistics Version 22.0.RESULTS： A total of 103 patients were included.The mean age was 51.2y.On multivariable analysis,each pre-operative positive deviation of 1 logMAR from a baseline VA of 0 logMAR was associated with a post-operative improvement of 0.859 logMAR （P〈0.001）.Likewise,an attached macula pre-operatively was associated with a 0.374 （P=0.003） logMAR improvement post vitrectomy.Absence of iris neovascularisation and absence of post-operative complications were associated with a post vitrectomy improvement in logMAR by 1.126 （P=0.001） and 0.377 （P=0.005） respectively.Absence of long-acting intraocular tamponade was associated with a 0.302 （P=0.010） improvement of logMAR post vitrectomy.CONCLUSION： Factors associated with visual improvement after vitrectomy are poor pre-operative VA,an attached macula,absence of iris neovascularisation,absence of post-operative complications and abstaining from use of long-acting intraocular tamponade.A thorough understanding of the factors predicting visual improvement will facilitate decision-making in vitreoretinal surgery.

关 键 词：玻璃体切除术 玻璃体出血 牵引性视网膜脱离 视觉预后 糖尿病性眼病 糖尿病性视网膜病变 

分 类 号：R587.2[医药卫生—内分泌]