张家港市中老年人血脂异常检出情况及危险因素分析  

Analysis on blood lipid abnormality and risk factors in middle-aged and old people in Zhangjiagang city

作　　者：李凯[1] 邱晶[1] 王夏冬 

机构地区：[1]张家港市疾病预防控制中心慢性病防制科,江苏张家港215600

出　　处：《现代预防医学》2017年第14期2549-2552,共4页Modern Preventive Medicine

基　　金：江苏省卫生厅预防医学科研项目(Y2012020);张家港市科技发展计划项目(ZKS1206)

摘　　要：目的了解张家港市211 715名50岁以上中老年人血脂异常的检出率及分布情况,探讨血脂异常与年龄、性别、体重指数、尿酸、血压、空腹血糖之间的相关性。方法从张家港市居民电子健康档案系统中导出2016年老年人健康体检数据库,对其中具有完整总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)检测数据的211 715名中老年人体检资料进行整理,根据不同变量需求确定样本量,分析血脂异常的检出率及分布情况;应用多因素Logistic回归分析血脂异常与年龄、性别、体重指数(BMI)、尿酸、血压、空腹血糖之间的相关性。结果 (1)211 715名中老年人血脂异常总体检出率为33.55%,男性检出率为31.14%,女性检出率为34.95%。以总体检人群作为标准人口,对年龄进行标化,男女血脂异常标化检出率分别为32.11%、35.34%,女性检出率高于男性。血脂异常检出率随年龄增长而呈现"先升后降"趋势(P<0.001)。(2)临床分型方面,高TC、高TG、混合型、低HDL-C的检出率分别为8.87%、16.11%、2.93%、10.61%,不同临床分型中女性检出率均高于男性(P<0.001)。(3)BMI过低及正常人群中,女性血脂异常检出率均高于男性(P<0.001);BMI超重人群男女检出率无差别;BMI肥胖人群中,男性检出率高于女性(P<0.001);血脂异常的检出率随着BMI的增加而呈现升高趋势(P<0.001)。(4)年龄、男性、高尿酸(HUA)、超重及肥胖、血压偏高、高空腹血糖(FBG)对血脂异常的风险度OR值(95%CI)分别为0.989(0.988~0.990)、0.811(0.795~0.828)、1.665(1.628~1.704)、1.549(1.517~1.581)、1.269(1.238~1.300)、1.438(1.406~1.471)。结论张家港市50岁以上中老年人血脂异常普遍流行,尤以高TG和女性群体为主;HUA、超重及肥胖、血压偏高、高FBG是50岁以上中老年人血脂异常的独立危险因素,而高龄、男性是其保护因素。Objective The aim of this study was to investigate the relationship between dyslipidemia and age, gender, body mass index, uric acid, blood pressure and fasting blood glucose in the middle-aged and old people over 50 years in Zhangjiagang city. Methods From the electronic health records system in Zhangjiagang city in 2016, elderly health examination database were analyzed, the total cholesterol （TC）, trig]yceride （TG）, low-density lipoprotein （LDL-C）, high density lipoprotein （HDL-C） were completed in 211715 elderly physical examination. The data of test was collected according to different demand variables to determine the sample size, the detection rate and the distribution of dyslipidemia. Multivariate logistic regression analyzed the relationship among dyslipidemia with age, gender, body mass index （BMI）, uric acid, blood pressure, and fasting blood glucose. Results （1）Among 211715 elderly dyslipidemia, total detection rate was 33.55%. The male detection rate was 31.14% and the female detection rate was 34.95%. The standardized detection rate of male and female dyslipidemia was 32.11% and 35.34%, respectively. And the detection rate of female was higher than that of male. （2） Clinical classification, high TC, high TG, mixed type, low HDL-C detection rate were 8.87%, 16.11%, 2.93%, 10.61%, respectively. In different clinical types, detection rate for female was higher than that for male （P〈0.001）. （3）The BMI was too low and female dyslipidemia detection rate in the normal population was higher than the male （P〈0.001）. There was no difference between men and women regarding overweight. For BMI obese, male incidence was higher than female （P〈 0.001）.The detection rate increased with the increase of BMI and increased lipid abnormalities （P〈O.001）. ~） For the age, male, high uric acid （HUA）, overweight and obesity, high blood pressure, high fasting blood glucose （FBG） on blood lipid, the risk value of OR （95%C/） were 0.989 （0.988 - 0.990）, 0

关 键 词：中老年人 血脂异常 危险因素 

分 类 号：R473.2[医药卫生—护理学]