前列腺绿激光汽化术治疗良性前列腺梗阻伴帕金森病的疗效  

Photoselective vaporization of the prostate for the treatment of benign prostatic obstruction in patients with Parkinson's disease

作　　者：崔萌[1] 郑冀鲁[1] 田思男 李连军[1] 张琦[1] 金讯波[1] 王慕文[1] CUI Meng ZHENG Jilu TIAN Sinan LI Lianjun ZHANG Qi JIN Xunbo WANG Muwen(Minimally Invasive Urology Center, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250014, Shandong, China)

机构地区：[1]山东大学附属省立医院泌尿微创中心,山东济南250014

出　　处：《山东大学学报（医学版）》2017年第7期100-102,109,共4页Journal of Shandong University:Health Sciences

基　　金：国家自然科学基金(81572534);山东省科技攻关项目(2014GSF118165)

摘　　要：目的研究经尿道前列腺绿激光汽化术(PVP)治疗良性前列腺梗阻(BPO)伴帕金森病(PD)的疗效及安全性。方法选择2008年7月至2016年5月收治的BPO伴PD患者20例,65~75岁,平均(69.85±3.12)岁,平均国际前列腺症状评分(IPSS)(23.40±5.89)分,平均最大尿流率(Qmax)(5.75±1.71)m L/s。患者均出现排尿困难症状并确诊为BPO伴PD,均排除合并多系统萎缩病(MSA),采用配对t检验进行组间比较,评估行PVP手术的疗效。结果 20例手术均顺利完成,平均手术时间(66.3±13.10)min,术后3个月患者平均IPSS(7.10±2.59)分,Qmax(14.03±4.40)m L/s,均较术前明显改善。4例患者术后出现急迫性尿失禁,经过盆底肌训练后好转。结论 PVP是BPO伴PD患者解除尿路梗阻及改善症状的一种安全有效的治疗方法。Objective To study the efficacy and safety of photoselective vaporization of the prostate （PVP） for the treatment of BPO in patients with PD. Methods A total of 20 patients with PD （excluding MSA）who underwent PVP for BPO were enrolled from July 2008 to May 2016. The average age was （69.85 ± 3. 12 ） years. The average IPSS was 23.40 ±5.89 and the average Qmax was （5.75 ± 1.71 ） mL/s. All patients were diagnosed as BPO with PD for dysuresia. Paired t test for comparison was used to evaluate the efficacy of PVP between the groups. Results All 20 patients underwent the surgeries successfully. The average operation time, IPSS and Qmax at the 3 months after surgery were （66.3 ± 13.10） minutes, 7.10 ±2.59 and （14.03 ±4.40） mL/s, respectively. Mild urge urinary incontinence occurred and voiding symptoms were improved after pelvic floor muscle training in 4 patients. Conclusion PVP is a safe and effective treatment for BPO in patients with PD.

关 键 词：良性前列腺梗阻 帕金森病 前列腺绿激光汽化术 

分 类 号：R699[医药卫生—泌尿科学]