改良麻醉方法对山羊麻醉效果的观察  

Observation of the anesthetic effects of an improved anesthetic method on goat

作　　者：李想[1] 张峰[1] 沈保卫 陈卫[1] 丁真奇[1] 

机构地区：[1]中国人民解放军第175医院骨科,漳州福建363000

出　　处：《中国比较医学杂志》2017年第6期46-48,共3页Chinese Journal of Comparative Medicine

基　　金：国家自然科学基金(编号:NSFC81371951);国家自然科学基金(编号:NSFC81401783)

摘　　要：目的通过与原有山羊麻醉方法的对比,观察改良后的麻醉方法的麻醉效果,为动物造模过程中的山羊麻醉提供理论和实践参考。方法选取制造胫骨骨折模型的山羊72只,36只采用原有麻醉方法即肌内注射速眠新联合地西泮(A组),36只采用改良后麻醉方法即肌内注射速眠新、地西泮联合泵注丙泊酚(B组)。观察山羊术中挣扎次数、追加速眠新总剂量、麻醉致死率及苏醒时间。结果 A组动物麻醉致死率为16.67%,B组无动物死亡;A组动物挣扎次数及追加速眠新总剂量、苏醒时间为均大于B组,差异有统计学意义(P<0.05)。结论改良后的麻醉方法可以减少动物的挣扎次数,减少麻醉药的用量,降低动物的死亡率。Objectives To observe the anesthetic effects of an improved anesthetic method on goat by comparing with the original method,and to provide theoretical and practical reference for anesthesia during the establishment of goat models. Methods A total of 72 goats were selected to make tibial fracture models,36 were enrolled as group A and others as group B. The group A was injected with Sumianxin and diazepam. The group B was injected with Sumianxin,diazepam and pumped propofol by intravenous pump. The times of animal struggle,total dose of additional Sumianxin,death rate,and recovery time were evaluated. Results The death rate of group A was 16. 67% and there was no death in the group B. The times of struggle,the total dose of additional Sumianxin and the recovery time of the group A were higher than group B,showing a significant difference（ P 〈0. 05）. Conclusions The improved anesthetic method can decrease the times of goat struggle times,reduce the dose of anaesthetics,and lower the death rate.

关 键 词：麻醉 速眠新 地西泮 丙泊酚 山羊 

分 类 号：R33[医药卫生—人体生理学]