重度妊娠期肝内胆汁淤积症对凝血功能的影响及诊治分析  

Effects of Severe Intrahepatic Cholestasis of Pregnancy on Blood Coagulation and Its Diagnosis and Treatment

作　　者：张小峰[1] 黄庆慧[1] 缪韵仪[1] 

机构地区：[1]福建医科大学附属宁德市医院产科,福建宁德352100

出　　处：《中国卫生标准管理》2017年第14期36-38,共3页China Health Standard Management

摘　　要：目的总结重度妊娠期肝内胆汁淤积症(Intrahepatic Cholestasis of Pregnancy,ICP)与凝血功能异常的关系及诊治方案。方法回顾性分析4例重度ICP合并凝血功能异常患者的诊治经过。结果重度ICP患者产后易感染,Fbg<1g/L终止妊娠,不利于产后恢复。结论 ICP患者应同时予以护肝、降胆汁酸治疗,重度ICP患者须及时终止妊娠,用高级别的抗生素预防感染。Objective To summarize the effects of ICP on coagulation function and the experience of diagnosis and treatment. Methods The diagnosis and treatment of 4 patients with cholestasis of pregnancy and coagulation disorders were retrospectively analyzed. Results Severe ICPpatients were susceptible to postpartum infection, when the Fbg was lower than 1 g/L, termination of pregnancy was not conducive to postpartum recovery. Conclusion Liver protection and bile acid lowering are equally important. Severe ICP patients should terminate the pregnancy in time, and use high-level antibiotics to prevent infection after birth.

关 键 词：重度妊娠期肝内胆汁淤积症 纤维蛋白原 总胆汁酸 

分 类 号：R714[医药卫生—妇产科学]