肺康复联合无创通气对慢阻肺急性加重患者生活质量的影响  

Effect of Kang Rehabilitation Combined with Noninvasive Ventilation on Quality of Life in Patients with Acute Exacerbation of Slow Resistant Lung

作　　者：葛南海 蔡孝桢 肖长长 谢黎丽 陈瑞宜 

机构地区：[1]广东医科大学附属厚街医院,广东东莞523960

出　　处：《广东微量元素科学》2017年第7期65-70,共6页Trace Elements Science

摘　　要：目的观察肺康复治疗在无创通气基础上对慢阻肺急性加重期患者肺功能指标、运动耐力、生活质量的影响。方法选择2014年10月—2016年10月于广东医科大学附属厚街医院住院的71例慢阻肺急性加重期患者作为研究对象,随机分为两组,对照组28例,观察组43例,对照组给予有效抗感染、吸入糖皮质激素+长效β2受体激动剂(ICS/LABA)及氧疗,无创辅助通气,观察组在对照组基础上给予肺康复治疗,比较两者患者在肺功能指标、运动耐力、生活质量的变化。结果 (1)两组患者治疗前肺功能指标(FEV1、FEV1/FVC(%)、FEV1%Pred(%))6MWD、CAT评分差异无统计学意义。(2)两组患者治疗后观察组FEV1高于对照组,但差异无统计学意义(P>0.05)。但治疗后第7天FEV1、FEV1/FVC(%)、FEV1%Pred(%)观察组高于对照组,差异有统计学意义;两组患者治疗后较治疗前6 min步行距离(6 MWD)明显升高,差异有统计学意义(P<0.05);CAT评分明显下降,差异有统计学意义(P<0.05)。(3)治疗后观察组6 MWD>对照组,差异有统计学意义(P<0.05);治疗后观察组CAT评分<对照组,差异有统计学意义(P<0.05),结论肺康复治疗联合无创通气能够明显改善COPD急性加重期患者运动耐力及生活质量,但肺通气功能指标FEV1无明显优于单用无创通气治疗。Objective To observe the pulmonary rehabilitation therapy on the basis of noninvasive ventilation in copd patients with acute aggravating period lung function index and sports endurance, the influence of the quality of life. Methods Selection in October 2014 to October 2016 in our hospital 71 cases of copd patients with acute aggravating period as the research object, were randomly divided into two groups, 28 cases in the control group and observation group 43 cases, control group given effective anti - infection to decide, long - acting inhaled corticosteroids ＋ 2 agonists （ICS/LABA） and oxygen cure,noninvasive assisted ventilation, observation group in the control group given on the basis of pulmonary rehabilitation treatment,compare the two patients in lung function index and sports endurance, the change of quality of life. Results （1） Both before treatment in patients with pulmonary function index （FEV1, FEV1/FVC （% ） , FEV1 （ % ） Mr Pred （ % ） 6 MWDS there was no statistically significant difference, the CAT score.（2） Observation group after treatment in patients with both FEV1 is higher than the control group, but there was no statistically significant difference P 〉 0. 05 ）. But the seventh day after the treatment of FEV1 , FEV1 /FVC（ % ） , FEV1 （%） Mr Pred （%） observation group is higher than the control group, the difference was statistically significant; two groups of patients after treatment than before treatment 6 minutes walking distance （6 MWDS） increased significantly, the difference was statistically significant （P 〈 0. 05） ; the CAT score decreased obviously, the difference was statistically significant （P 〈0. 0 5 ）.（3） The observation group after treatment 6 MWDS 〉 the control group, the difference was statistically significant （ P 〈 0. 05 ） ; after treatment to observe the CAT score 〈 control group, the difference was statistically significant （P 〈0

关 键 词：COPD 肺康复治疗 无创通气 肺功能 6 MWD 

分 类 号：R563[医药卫生—呼吸系统]