普适型纸芯片的研究与应用  

Paper-based Analytical Devices with General Applicability

作　　者：张跃[1] 贺军辉[1] 

机构地区：[1]中国科学院理化技术研究所光化学转换与功能材料重点实验室微纳材料与技术研究中心功能纳米材料实验室,北京100190

出　　处：《影像科学与光化学》2017年第4期506-515,共10页Imaging Science and Photochemistry

基　　金：国家自然科学基金项目(21571182);中国科学院理化技术研究所创新人才培育基金(2014-Z)资助

摘　　要：纸基分析芯片(纸芯片)具有成本低、便携化、操作和后处理简单无污染等优点,在临床诊断、食品质量控制和环境监测等领域有着广阔的应用前景。然而,由于难以制作性能优异的疏脂性屏障,使得纸芯片在涉及有机溶剂和表面活性剂的分析检测中,其发展受到了限制。针对当前纸芯片开发研究中存在的灵敏度较低、对有机溶剂和表面活性剂敏感等难点问题,研究人员在滤纸基底上制作出了性能优异的疏水隔离图案和高粘附疏水表面,并验证了所制备的纸芯片对涉及有机溶剂和表面活性剂的分析检测具有普适性。本文对此类普适型纸芯片的研究与应用进行评述。Paper-based analytical devices （PADs） show great prospects in clinical diand environmental monitoring due to their intrinsic advantages such as low cost, portability, and easy operation and post-treatment without cross contamination. Nevertheless , present PADs often suffer frosensitivity and are generally not applicable to analyses involving organic solvents or surfactant solutions due to the difficulties in fabricating lipophobic barriers. To address these issues , researchers fabricated high performance paper-based hydrophobic patterns and highly adhesive hydrophobic surfaces and defabricated PADs possess general applicability for assays involving organic solvents and surfactants. This reviewwill introduce these reports on the study and applications of PADs with general applicability.

关 键 词：纸芯片 显色分析 重金属离子检测 细菌分析 

分 类 号：TS761.2[轻工技术与工程—制浆造纸工程]