子痫前期与女性远期心血管疾病的关系研究进展  

Progress on the relationship between preeclampsia and long-term cardiovascular disease among women

作　　者：闫海洋[1] 蔡伟[1] 孙圣凯[2] 乔娅楠 王志宏[2] 李玉明[1] Yan Haiyang Cai Wei Sun Shengkai Qiao Yanan Wang Zhihong Li Yuming(Institute of Cardiovascular Diseases and Heart Center ,Affiliated Hospital of Logistics University of the Chinese People＇s Armed Police Forces, Tianjin 300162, China)

机构地区：[1]中国人民武装警察部队后勤学院附属医院心血管病研究所,天津300162 [2]中国人民武装警察部队后勤学院附属医院心医教部,天津300162 [3]中国人民武装警察部队后勤学院学员二旅

出　　处：《中国综合临床》2017年第4期377-380,共4页Clinical Medicine of China

基　　金：天津市科技计划项目（15ZXJZSY00010）;天津市科技计划项目（16ZXMJSY00130）

摘　　要：子痫前期是妊娠女性特有的一种疾病,有子痫前期病史的女性远期患发心血管疾病的风险明显增加.子痫前期的病因和发病机制目前还尚不明确,其与心血管疾病可能有着共同的病理生理机制,如氧化应激、血管内皮损伤、胰岛素抵抗、脂代谢紊乱等.本文就子痫前期与女性远期心血管疾病的关系,尤其是冠心病、高血压、脑卒中进行探讨分析,寻找两者之间的关联因素,为这些有子痫前期病史的高危女性远期心血管疾病风险管理提供依据.以子痫前期为切入点阻断、干预和防范女性心血管疾病,将防治关口前移,将为全球超过3亿子痫前期女性的心血管疾病防控提供一个难得的机遇.Preeclampsia（PE） is a unique disease to pregnancy women,and women who had a history of preeclampsia significantly increased the risk of cardiovascular disease.Preeclampsia etiology and pathogenesis is not clear yet,it may have common pathophysiology with cardiovascular disease（CVD）,such as oxidative stress,endothelial injury,insulin resistance,lipid metabolic disorder and so on.The article reviewed the relationship between preeclampsia and long-term cardiovascular disease among women,especially discussed the disease such as coronary heart disease,hypertension and stroke,to find the association and to explore the potential risk management options for these high-risk women.To block,intervene,and prevent cardiovascular disease starting with preeclampsia,it is of significance to the cardiovascular health of over 300 million women worldwide.

关 键 词：子痫前期 心血管疾病 风险管理 

分 类 号：R54[医药卫生—心血管疾病]