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机构地区:[1]武汉大学基础医学院药理系,湖北武汉430071 [2]南昌市第九医院普外科,江西南昌330002
出 处:《武汉大学学报(医学版)》2017年第5期837-840,共4页Medical Journal of Wuhan University
摘 要:目的:分析南方某中学阑尾炎爆发病例的特征以及爆发的原因。方法:调查阑尾炎爆发的人群和时间分布及暴露因素,复习爆发病例的病历和病理切片。结果:2005年1月-2006年12月间该校出现阑尾炎病例36名,男女生的发病率分别为1.9%和8.6%(Z=3.67,P<0.01)。男女生的生活习惯不同。病例常成簇出现,病例间常有接触史。极少数病例体温、白细胞和中性粒细胞百分比增高。所有病例组织学诊断为急性单纯性阑尾炎,组织学改变的特征为阑尾组织出血、淋巴细胞和嗜酸细胞浸润。结论:爆发病例是"非穿孔性阑尾炎"实体,可能由传染因子所致。Objective:To analyze the features of patients with appendicitis in outbreak at a middle school in southern China and cause of the outbreak.Methods:Epidemic data,medical records,and histological slides of resected appendices were examined.Results:During period between January,2005 and December,2006,of thirty-six patients with appendicitis occurred in clustering pattern among 706 students with higher frequency in female students(8.6%)than male students(1.9%)(Z=3.67,P〈0.01).Many patients had a history of mutual contact before the onset of symptom.Few patients had elevated temperature,white blood cells and neutrophil.All patients were diagnosed as acute simple appendicitis.The histological examination exhibited diffuse or focal hemorrhages in the lamina propria or within hyperplastic lymphoid follicles,and infiltration of eosinophils and lymphocytes.Conclusion:The patients occurring in the outbreak at the school suffered from "nonperforated appendicitis"which may be caused by infectious agents.
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