银杏达莫注射液对急性冠脉综合征患者脂代谢、血小板聚集性的影响  

Effect of Ginkgo Dipyidamolum Injection on Lipid Metabolism and Platelet Aggregation in Patients with Acute Coronary Syndrome

作　　者：赵志强 郭敬玲 ZHAO Zhi-qiang GUO Jing-ling.(Department of Medicine, Huixian Public Hospital, Huixian 453600, Henan Province, Chin)

机构地区：[1]河南省辉县市公费医疗医院内一科,河南辉县453600

出　　处：《罕少疾病杂志》2017年第4期15-16,24,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的分析急性冠脉综合征(ACS)经银杏达莫注射液治疗的效果,并探讨该药物对病患血小板聚集、脂代谢的影响。方法选择我院收治的90例急性冠脉综合征病患进行研究,随机分为A、B组各45例。A组给予常规西药治疗,B组在此基础上加用银杏达莫注射液治疗,比较两组心绞痛疗效、血小板聚集率、血脂水平、不良反应。结果 (1)心绞痛改善有效率:B组为95.56%,A组为80.00%,B组有效率比A组更高,具有差异性(P<0.05);(2)B组治疗后的血脂水平明显改善,与A组(均低于A组)比较有统计学意义(P<0.05);(3)B组经治疗后,血小板聚集率下降,低于A组,组别间比较有差异(P<0.05);(4)不良反应率:B组(4.44%)与A组(2.22%)相比无差异性(P>0.05)。结论 ACS患者采用银杏达莫注射液治疗,能缓解心绞痛症状,改善血小板聚集率以及脂代谢,值得临床推广。Objective To analyze the effect of ginkgo dipyidamolum injection in the treatment of acute coronary syndrome （ACS）, and explore its influence on lipid metabolism and platelet aggregation. Methods A total of 90 patients with acute coronary syndrome in our hospital were were taken as the clinical research objects, and they were randomly divided into A group （45 cases） and B group （45 cases）. Both groups were treated with conventional western medicine, besides, the B group was given additional ginkgo dipyidamolum injection. The improvement of angina pectoris, platelet aggregation rates, lipid levels and adverse reactions in the two groups were compared. Results The effective rate of angina pectoris improvement in the B group was 95.56% which was higher than that in the A group 80.00%, and their difference was statistically significant（P〈0.05）. After treatment,the lipid level in the B group was obviously improved, and it was significantly lower than that in the A group（P〈0.05）, the platelet aggregation rate in the B group was decreased, and it was significantly lower than that in the A group （P〈0.05）. The adverse reaction rates in the B and A group were respectively 4.44% and 2.22%, the difference between the two groups was not statistically significant（P〉0.05）. Conclusion Ginkgo dipyidamolum injection can not only relieve angina symptoms in ACS patients, but also improve platelet aggregation rate and lipid metabolism. Thus, it is worthy of application in clinic.

关 键 词：血小板聚集 脂代谢 ACS 银杏达莫 

分 类 号：R331.143[医药卫生—人体生理学]