吉林省成人甲状腺疾病流行病学研究  

Epidemiological study on adult thyroid disease in Jilin Province

作　　者：陈慧欣[1] 战大伟[1] 冯宝香[1] 李维[1] 刘铁军[1] 翟俊民[1] 王雪[1] 孙慧[1] 罗艳华[1] CHEN Hui-xin ZHAN Da-wei FENG Bao-xiang LI Wei LIU Tie-jun ZHAI Jun-min WANG Xue SUN Hui LUO Yan-hua(Jilin Provincial No. 2 Institute for Endemic Disease Control and Research, Jilin 132001, China)

机构地区：[1]吉林省地方病第二防治研究所,吉林吉林132001

出　　处：《中国地方病防治》2017年第3期241-244,共4页Chinese Journal of Control of Endemic Diseases

摘　　要：目的吉林省于2000年实现消除碘缺乏病阶段目标后,通过实施食盐加碘为主防治措施,全省碘缺乏病得到了有效控制。为了摸清在碘缺乏病病情有效控制下,全省成人甲状腺疾病患病现状,开展了此项研究。方法采用按人口比例概率抽样方法(PPS法),在全省采取连续抽样方法,确定30个县(市、区),从抽到的县(市、区)随机抽取一个乡(镇、街道),在每个乡(镇、街道)辖区内随机抽取一个村,在每个村中随机抽取80名20-60岁居民,男女各半进行甲状腺疾病筛查。结果全省9个市(州)30个县(市、区)共抽检20-60成人3007人,各种甲状腺疾病患病率依次为:甲状腺结节683例,患病率为22.71%;亚临床甲亢96例,患病率为3.19%;亚临床甲减81例,患病率为2.69%;临床甲亢56例,患病率为1.86%;临床甲减34例,患病率为1.13%;甲状腺癌21例,患病率为0.70%;甲状腺炎8例,患病率为0.27%;甲状腺球蛋白抗体阳性率为9.25%;抗甲状腺过氧化物酶抗体阳性率为12.04%。结论全省成人甲状腺疾病总体患病率为32.56%,共检出7种甲状腺疾病,其中,以甲状腺结节为高发为22.7%,其它依次为亚临床甲亢、亚临床甲减、临床甲亢、临床甲减、甲状腺癌和甲状腺炎;患病率与临床接诊情况相符;甲状腺疾病患病率性别比,女性患病总体高于男性,男∶女为1∶1.67;从年龄段患病情况看,甲状腺疾病患病随着年龄的增长甲状腺疾病患病率逐渐增加;地区之间、城乡之间患病率无显著差异;全省成人甲状腺疾病发病呈散在分布,不存在聚集性。Objective After the elimination of iodine deficiency disorders（ IDD） in 2000, IDD had been effectively controlled through the implementation of iodized salt prevention and control measures in Jilin Province. The investigation was carried out in order to find out the prevalence of thyroid disease in the province under the effective control of IDD.Methods By population proportion sampling（ PPS）,selected 30 counties（ cities, districts）; in each county, a township（ town, street） was randomly selected; in each township, a village was selected. Finally,randomly selected 80 residents（ male and female were half each） aged from20 to 60 from each village as the samples.Results A total of 3 007 people（ from 30 townships within 9 cities in the province）were sampled in this investigation. The prevalence rates of various thyroid diseases were as follows： 683 cases of thyroid nodules,the prevalence rate is 22.71%; 96 cases of subclinical hyperthyroidism, the prevalence rate is 3.19%; 81 cases of subclinical hypothyroidism, the prevalence rate is 2.69%; 56 cases of hyperthyroidism, the prevalence rate is 1.86%; 34 cases of clinical hypothyroidism, the prevalence rate is 1.13%; 21 cases of thyroid cancer, the prevalence rate is 0.70%; 8 cases of thyroid gland,the prevalence rate is 0. 27%; the positive rate of thyroglobulin antibody is 9. 25% and anti-thyroid peroxidase antibody is 12.04%.Conclusion The total prevalence rate of adult thyroid disease in the province is 32.56%, and 7 kinds of thyroid diseases are detected. Among them, the thyroid nodules disease occupies the highest incidence of 22.7%,followed by other subclinical hyperthyroidism, sub clinical hypothyroidism, hyperthyroidism, hypothyroidism, thyroid cancer and thyroid. Moreover, the prevalence rate and clinical admissions are consistent with each other. According to the prevalence of thyroid disease sex ratio, the prevalence of women is higher than that of men, the proportion was 1： 1.67. Moreover, from the age prevalence situation, thyr

关 键 词：成人 甲状腺疾病 患病 

分 类 号：R581[医药卫生—内分泌]