2016年沧州市水源性高碘地区儿童甲状腺肿病情现状调查  

Surveillance on thyroid goiter status in water-borne high iodine areas in Cangzhou City in 2016

作　　者：李顺利[1] 温松臣[1] 吕胜敏[2] 祁业敏[1] 王琳琳[1] 孙宏轩 黄志红 LI Shun-li WEN Song-chen LV Sheng-min QI Ye-min WANG Lin-lin SUN Hong-xuan HUANG Zhi-hong(Cangzhou Municipal Center for Disease Prevention and Control, Cangzhou 061001, China)

机构地区：[1]沧州市疾病预防控制中心,河北061001 [2]河北省疾病预防控制中心地方病防治所 [3]吴桥县疾病预防控制中心

出　　处：《中国地方病防治》2017年第3期251-253,共3页Chinese Journal of Control of Endemic Diseases

摘　　要：目的了解停供碘盐后沧州市目前水源性高碘地区儿童甲状腺肿病情,为制定防治措施提供科学依据。方法按《全国碘缺乏病监测方案》在沧州市10个水源性高碘县(市、区)进行居民无碘食盐检测;在水碘含量100.0-1 100.0μg/L范围内抽取9个水源性高碘病情监测点,每个监测点随机抽取8-10岁儿童100名,其中,男、女各50名;用B超法检测甲状腺容积;随机抽取其中不少于50名儿童(男、女各半)检测尿碘含量;每个监测村采集2份末梢水水样,测定水碘含量;学校饮用净化水的采集1份水样,测水碘含量。结果 10个高碘县(市、区)共采集居民户食用盐2 580份,其中,无碘食盐2 416份,无碘食盐率为93.64%;9个水源性高碘病情监测点对925名儿童进行了甲状腺容积检测,甲状腺肿大116例,总甲肿率为12.54%,采集儿童尿样542份,尿碘中位数为536.0μg/L;水碘值在100.0-500.0μg/L的监测点儿童甲肿率与水碘值在500.0-1 096.0μg/L的监测点儿童甲肿率具有统计学差异(χ2=40.17,Ρ<0.01)。结论水源性高碘地区停供碘盐措施后,水碘值在100.0-500.0μg/L的监测点儿童甲肿病情较轻,水碘值≥500.0μg/L的地区病情仍较为严重。Objective To understand children＇s goiter status in water-borne high iodine areas in Cangzhou City so as to provide scientific basis for formulating control strategy for high iodine.Methods Monitoring of non-iodine salt was undertaken in 10 high iodine counties in Cangzhou City according to the National Plan of IDD Surveillace. Ten monitoring sites were selected from villages with water iodine ranging from 100.0 μg/L to 1 100.0 μg/L. In each monitoring site, 100 school children（ half male and half female） were selected to measure their thyroid size by ultrosound and more than half of them were asked to provide urine samples to detect iodine content. Two household water samples were collected to detect iodine content in each village. One purified water sample was collected in each school with purified water supply.Results In the 10 high iodine counties,2 580 edible salts were gathered and detected with 2 416 identified as non-iodine,accounting for 93.64%. In the 9 monitoring sites, 925 children were undertaken thyroid ultrasound measurement and 116 cases of goiter were identified with total prevalence being 12.54%. A total of542 urine samples were collected with median urinary iodine being 536. 0 μg/L. There was a significant difference between the goiter prevalence in monitoring site with water iodine being 100 ~ 500 μg/L and that in monitoring site with water iodine being 500~ 1 096.0 μg/L（ P〈0.01）.Conclusions After removing iodized salt in high water iodine areas, children＇s goiter prevelace was relatively lower in monitoring sites with water iodine being 100 ~ 500 μg/L, and higher in monitoring site with water iodine being500 ~ 1 096.0 μg/L.

关 键 词：水碘 甲状腺肿大 尿碘 

分 类 号：R581.3[医药卫生—内分泌] R591.1[医药卫生—内科学]