综合营养干预对2型糖尿病患者胰岛素敏感性影响分析  

Effect of Comprehensive Nutrition Intervention on Insulin Sensitivity in Patients with Type 2 Diabetes Mellitus

作　　者：王尊[1] 何书励[2] 李振水[3] 贾凯[4] 宋新[4] 段云卉[4] 许英霞[3] 郝春满[3] 刘思彤[1] 

机构地区：[1]首都医科大学附属北京同仁医院营养科,北京100730 [2]中国医学科学院北京协和医院营养科,北京100730 [3]首都医科大学附属北京天坛医院营养科,北京100050 [4]首都医科大学附属北京朝阳医院营养科,北京100020

出　　处：《中国食物与营养》2017年第7期80-83,共4页Food and Nutrition in China

摘　　要：目的:了解综合营养干预对2型糖尿病患者血清胰岛素敏感性影响。方法:选取前往医院就诊的2型糖尿病患者98人,随机分为干预组、对照组。对干预组人群开展为期6个月的膳食指导和符合营养制剂补充的综合营养干预,对照组不采取相应干预措施。结果:至干预结束后,干预组不同时点血清胰岛素浓度平均减少1.53m IU/L,而对照组平均增加2.27m IU/L,差异有统计学意义,P<0.05;干预组胰岛素抵抗指数减少0.04±3.70,而对照组增长0.12±3.76,差异有统计学意义,P<0.05。结论:综合营养干预对2型糖尿病患者血清胰岛素敏感性可起到一定程度的改善作用。【Objective】To investigate the effect of comprehensive nutrition intervention on serum insulin sensitivity in patients with type 2 diabetes mellitus. 【Method】Totally 98 Male patients with type 2 diabetes mellitus were randomly divided into intervention group and control group. A total of 6 months of dietary guidance and nutritional supplement supplemented with nutritional supplements were conducted in the intervention group,and the control group did not take the appropriate intervention. 【Result】At the end of the intervention,the serum insulin concentration decreased by 1. 53 m IU/L and 2. 27 m IU/L in the control group at the same time,the difference was significant,（ P 0. 05）. The insulin resistance index decreased by 0. 04 ±3. 70 at the same time and increased 0. 12 ±3. 76 in the control group at the same time,the difference was significant（ P 0. 05）. 【Conclusion】Comprehensive nutritional intervention can improve the serum insulin sensitivity in patients with type 2 diabetes mellitus.

关 键 词：综合营养 干预 2型糖尿病 胰岛素 

分 类 号：R459.3[医药卫生—治疗学] R587.1[医药卫生—临床医学]