毛脉酸模果实乙酸乙酯部位化学成分研究  

Chemical Constituents of Ethyl Acetate Extract from Rumex Gmelini Fruit

作　　者：徐明远[1] 王谦博[2] 卫丽曼[3] 郭盛磊[1] 丁常宏[1] 王振月[1] XU Ming - yuan WANG Qian - bo WEI Li - man GUO Sheng - lei DING Chang - hong WANG Zhen - yue(Heilongjiang University of Chinese Medicine, Harbin 150040, China Pharmacy Department of the First Affiliated Hospital of Guangdong Medical University, Guangzhou 510000, China Yangtze River Pharmaceutical Group Co. Ltd. , Taizhou 225321, China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]广东药科大学附属第一医院药学部,广东广州510000 [3]扬子江药业集团有限公司,江苏泰州225321

出　　处：《中医药信息》2017年第4期22-26,共5页Information on Traditional Chinese Medicine

基　　金：国家自然科学基金项目(No.30970300);哈尔滨市科技创新人才研究专项基金项目(No.2010rfxxs031)

摘　　要：目的:研究毛脉酸模果实乙酸乙酯部位的化学成分。方法:采用硅胶柱色谱和Sephadex-LH20柱色谱技术对毛脉酸模果实乙酸乙酯部位化学成分进行分离纯化,运用波谱分析技术鉴定化合物结构。结果:从毛脉酸模果实乙酸乙酯部位中分离得到了8个化合物,分别鉴定为:1)3-O-甲基槲皮素,2)槲皮素,3)胡萝卜苷,4)大黄素,5)黄素甲醚-8-O-β-D-葡萄糖苷,6)大黄酚-8-O-β-D-葡萄糖苷,7)白藜芦醇,8)大黄酚。结论:3-O-甲基槲皮素首次在酸模属植物中分离得到,槲皮素和大黄素甲醚-8-O-β-D-葡萄糖苷首次在毛脉酸模中分离得到。Objective ： To study the chemical constituents of Rumex gmelini. Methods ： Chemical constituents of the ethyl acetate extract from Rumex gmelini fruit was purified by silica gel and Sephadex - LH20 chromato- graphic columns, and the compounds structures were identified by using spectral analysis techniques. Results： Eight compounds were isolated in ethyl acetate extract from Rumex gmelini fruit. They were identified as： 3 - O -methyl quercetin, quercetin, daucosterol, emodin, physcion major beta D glucoside, chrysophanol major beta D glucoside, resveratrol, and chrysophanol. Conclusion ：3 - O - methyl quercetin was isolated for the first time in Rumex plants, also quercetin and physcion major beta D glucoside were first obtained in Rumex gmelini.

关 键 词：毛脉酸模 果实 化学成分 乙酸乙酯 

分 类 号：R284.1[医药卫生—中药学]