择期脑肿瘤切除术患者手术部位感染危险因素  

Risk factors for surgical site infection in patients undergoing selective brain tumor resection

作　　者：谢培彦[1] 李元晖[1] 唐玉梅[1] 陈解语[1] 

机构地区：[1]广西壮族自治区人民医院,广西南宁530021

出　　处：《中国感染控制杂志》2017年第7期650-653,共4页Chinese Journal of Infection Control

摘　　要：目的探讨择期脑肿瘤切除患者手术部位感染的危险因素,为临床防治提供依据。方法前瞻性监测2013年4—9月及2014年4—9月某院神经外科进行择期脑肿瘤切除术的患者,制定监测方案及个案调查表,收集其基本资料、手术情况、术后感染症状/体征及实验室检查结果、感染有关因素、抗菌药物使用情况等,并分析其感染危险因素。结果共调查205例患者,其中23例发生手术部位感染,发病率为11.22%;单因素分析结果显示,身体质量指数(BMI)、NNIS评分、脑脊液漏与手术部位感染的发生有关(均P<0.05);logistic回归分析显示,NNIS评分高、脑脊液漏是择期脑肿瘤切除术患者手术部位感染发生的独立危险因素(均P<0.05)。结论择期脑肿瘤切除术患者手术部位感染发病率较高,在临床工作中,应针对包括脑脊液漏在内的不同危险因素采取相应的预防措施。ObjectiveTo explore the risk factors of surgical site infection（SSI） in patients undergoing selective brain tumor resection, and provide reference for clinical prevention and treatment.MethodsPatients who underwent selective brain tumor resection in the neurosurgery department of a hospital during AprilSeptember 2013 and AprilSeptember 2014 were monitored prospectively, monitoring programme and individualized questionnaire were formulated, the basic data, operation condition, postoperative symptoms/signs, laboratory test results, infectionrelated factors, and antimicrobial use in patients were collected, risk factors for infection were analyzed. ResultsA total of 205 patients were investigated, 23 （11.22%） of whom had SSI; univariate analysis showed that body mass index （BMI）, NNIS score, and cerebrospinal fluid leakage were related to the occurrence of SSI（all P〈0.05）; logistic regression analysis showed that high NNIS score and cerebrospinal fluid leakage were independent risk factors for SSI in patients undergoing selective brain tumor resection（both P〈0.05）. ConclusionIncidence of SSI is higher in patients with selective brain tumor resection, corresponding preventive measures should be taken according to different risk factors including cerebrospinal fluid leakage.

关 键 词：脑肿瘤 脑肿瘤切除术 手术部位感染 危险因素 脑脊液漏 身体质量指数 

分 类 号：R619.3[医药卫生—外科学]