一起群体性溴敌隆中毒事件调查  

An investigation of a mass incident of bromadiolone poisoning

作　　者：张帅[1,4] 李其禄[1,2] 菅向东[1,2] 王珂[1,3] 吴强[1,5] 徐勤亮[6] 高蓓钧 张波[4] Zhang Shuai Li Qilu Jian Xiangdong Wang Ke Wu Qiang Xu Qinliang Gao Beijun Zhang Bo(Department of Poisoning ＆ Occupational Diseases of Shandong university Qilu hospital, Jinan 250012, China)

机构地区：[1]山东大学齐鲁医院急诊科中毒与职业病科,济南250012 [2]山东大学校医院 [3]山东大学公共卫生学院 [4]章丘市人民医院急诊科 [5]蚌埠医学院第一附属医院ICU [6]临沂市人民医院急诊科

出　　处：《中华劳动卫生职业病杂志》2017年第5期356-357,共2页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：2012年国家临床重点专科建设项目（2012650）;泰山学者建设工程专项经费项目（ts20130911）;山东省医药卫生重点实验室（鲁卫科教国合字[2013]49号）

摘　　要：目的对一起群体溴敌隆中毒事件进行调查并对其临床资料进行分析。方法对2015年12月发生在山东某地的一起群体溴敌隆中毒事件进行调查，同时对其临床资料进行分析总结。结果本事件是一起由投毒引起的群体溴敌隆中毒事件，中毒患者以出血及凝血功能障碍为主要临床表现，经过综合抢救治疗特别是使用维生素K1静脉滴注治疗，全部患者治愈。结论溴敌隆中毒可以引起严重的内脏出血及凝血功能障碍，静脉滴注维生素K1具有很好的疗效。Objective To investigate a mass incident of bromadiolone poisoning and analyze related clinical data. Methods An investigation was performed for a mass incident of bromadiolone poisoning in a place in Shandong, China in December 2015, and related clinical data were analyzed and summarized. Results This incident was a mass incident of bromadiolone poisoning caused by spreading poison. The poisoned patients had major clinical manifestations of bleeding and coagulation disorder and all of them were cured after comprehensive rescue, especially after intravenous drip of vitamin K1. Conclusion Bromadiolone poisoning can cause severe visceral hemorrhage and coagulation disorder, and intravenous drip of vitamin K1 has a good therapeutic effect.

关 键 词：溴敌隆 中毒 事故 

分 类 号：R595.4[医药卫生—内科学]