海水养殖环境细菌耐药性的危害  

Harmfulness of Bacterial Antibiotic Resistance from Maricultural Environments

作　　者：党宏月[1] 宋林生[1] 张志南[2] 

机构地区：[1]中国科学院海洋研究所,青岛266071 [2]中国海洋大学,青岛266003

出　　处：《海洋科学集刊》2006年第1期29-40,共12页Studia Marina Sinica

基　　金：国家自然科学基金(编号:40476058和40576069);中国科学院海洋研究所引进人才启动经费(编号:LSC2-3-1)联合资助。

摘　　要：Antibiotics have been the key chemotherapeutic agents used in maricultural settings to achieve either prophylaxis or therapy. During the last 10 years, the world-wide frequent outbreak of maricultural animal diseases caused by microbes has resulted in extensive and intensive use and misuse of antibiotics. As a harmful side effect, antibiotic resistant bacteria, especially those with multi-drug resistance, are abundant and persistent in marine environments, causing even higher level of difficulty and failure in aquacultural disease control and treatment. Furthermore, via the food chain, interactions of land and ocean, and human maritime activities, antibiotic resistance can be transferred to and spread in healthy marine and terrestrial environments, putting human health and wellbeing at great risk. Thus, maricultural environments, as a cause, reservoir and dissemination source of antibiotic resistance, call for our immediate attention and investment of research efforts.Antibiotics have been the key chemotherapeutic agents used in maricultural settings to achieve either prophylaxis or therapy. During the last 10 years, the world-wide frequent outbreak of maricultural animal diseases caused by microbes has resulted in extensive and intensive use and misuse of antibiotics. As a harmful side effect, antibiotic resistant bacteria, especially those with multi-drug resistance, are abundant and persistent in marine environments, causing even higher level of difficulty and failure in aquacultural disease control and treatment. Furthermore, via the food chain, interactions of land and ocean, and human maritime activities, antibiotic resistance can be transferred to and spread in healthy marine and terrestrial environments, putting human health and wellbeing at great risk. Thus, maricultural environments, as a cause, reservoir and dissemination source of antibiotic resistance, call for our immediate attention and investment of research efforts.

关 键 词：耐药性研究 海水养殖 耐药基因 耐药因子 抗生素滥用 质粒介导 耐药机理 耐药微生物 耐药质粒 遗传 

分 类 号：S94[农业科学—水产养殖]