迟缓爱德华氏菌及其致病机理  

EDWARDSIELLA TARDA AND ITS PATHOGENESIS

作　　者：王波[1] 莫照兰[1] 

机构地区：[1]中国科学院海洋研究所

出　　处：《海洋科学集刊》2007年第1期133-139,共7页Studia Marina Sinica

基　　金：国家973计划(2006CB101803);国家863计划(2006AA100310);国家自然科学基金(30671613)资助

摘　　要：Edwardsiella tarda is a gram-negative pathogen with a wide host range, which can infect many kinds of fish and lead to extensive losses in aquaculture. The pathogenesis of E. tarda is not clearly understood. So far as we know its virulence factors include hemolysins, chondroitinases, dermatonecrotic exotoxic substances, catalases, etc. The latest study indicates that the type three secretion system (TTSS) of E.tarda is tightly associated with bacterial pathogenesis. The gene structure of the TTSS has been elucidated and relational research is on the way.Edwardsiella tarda is a gram-negative pathogen with a wide host range, which can infect many kinds of fish and lead to extensive losses in aquaculture. The pathogenesis of E. tarda is not clearly understood. So far as we know its virulence factors include hemolysins, chondroitinases, dermatonecrotic exotoxic substances, catalases, etc. The latest study indicates that the type three secretion system (TTSS) of E.tarda is tightly associated with bacterial pathogenesis. The gene structure of the TTSS has been elucidated and relational research is on the way.

关 键 词：爱德华氏菌 溶血素 坏死毒素 鳖爱德华氏菌病 致病菌株 鞭毛蛋白 致病因子 外膜蛋白 鲻鱼 丽鲷 

分 类 号：S941[农业科学—水产养殖]