重症手足口病患儿捐献供肾用于成人受者肾移植的疗效观察  

Reports of 5 cases of kidney transplantation from donors with severe hand-foot-mouth disease

作　　者：高陈[1] 吴碧琛[2] 蓝恭斌[1] 彭风华[1] 余少杰[1] 郭勇[1] 彭龙开[1] 

机构地区：[1]中南大学湘雅二医院泌外器官移植科,长沙410011 [2]湖南省儿童医院呼吸科

出　　处：《中华器官移植杂志》2017年第3期141-144,共4页Chinese Journal of Organ Transplantation

摘　　要：目的 探讨重症手足口病婴幼儿捐献供肾用于成人肾移植的临床疗效和安全性.方法 2014年1月至2016年12月间5例成人受者接受重症手足口病患儿捐献供肾移植,受者年龄为（26～41）岁,体质量为（50～59） kg.3例捐献患儿的年龄分别为2岁、2岁1个月、3岁11个月,体质量分别为11kg、10 kg、15kg.1例受者接受分离式双肾移植,其余4例接受单肾移植.结果 5例中,除1例因肾动脉血栓形成在术后第5天切除移植肾,其余4例受者均获得了满意的临床疗效,术后随访期间均未出现手足口病相关症状.结论 重症手足口病婴幼儿捐献供肾可以用于成人肾移植,临床效果良好.Objective To investigate the clinical effect and safety of kidney transplantation from donors with severe hand-foot-mouth disease （HFMD）.Methods Five cases of kidney transplantation from three donors with HFMD between Jan.2014 and Dec.2016 were analyzed.The age of three donors was 2 years,2 years and one month,and 3 years and 11 months respectively,and body weight was 11 kg,10 kg and 15 kg respectively.The age of recipients ranged from 26 to 41 years and weight from 50 to 59 kg.Single kidney transplantations were performed on 4 cases,and dual separating kidney transplantation on one case.Results One case of the transplantations was failure due to the allograft artery thrombosis.The rest 4 cases gained satisfied clinical effect.None of the 5 cases showed any symptoms associated with HFMD.Conclusion The clinical effect of kidney transplantation from donors with severe HFMD is satisfactory.The organs from donors with severe HFMD could only be used by adult recipients.

关 键 词：肾移植 供者 手足口病 

分 类 号：R699.2[医药卫生—泌尿科学]