YL-1型针引流联合尿激酶冲洗在慢性硬膜下血肿中的治疗效果  

Therapeutic effect of YL-1 needle drainage combined with Urokinase rinsing on treating chronic subdural hematoma

作　　者：林运全[1,2] 郭大华 郑泽洲 许奕聪 王能强 

机构地区：[1]汕头大学医学院第一附属医院神经外科,广东汕头515041 [2]广东省汕头潮南民生医院神经外科,广东汕头515144

出　　处：《中国当代医药》2017年第20期48-51,共4页China Modern Medicine

摘　　要：目的分析YL-1型针引流联合尿激酶冲洗在慢性硬膜下血肿中的治疗效果。方法选择我院神经外科2012年3月~2016年5月收治的92例慢性硬膜下血肿患者作为研究对象,计算机随机分为常规组与实验组。常规组患者采取单纯钻孔引流法治疗,实验组给予YL-1型针引流联合尿激酶冲洗治疗,对比两组治疗效果。结果实验组与常规组患者的治疗总有效率分别为97.83%与84.78%(P<0.05);实验组血肿消失时间、残存硬膜下积液率、血肿复发率分别为(7.22±2.12)d、2.17%、0.00%,均明显优于常规组(P<0.05);治疗前两组患者的生存质量评分无明显差异(P>0.05);治疗后实验组患者生存质量评分均明显优于常规组(P<0.05)。结论对慢性硬膜下血肿患者采取YL-1型针引流联合尿激酶冲洗治疗的临床疗效显著,可有效降低血肿复发率,具有手术安全性高、创伤小、简便易行等优势,可帮助患者提高生存质量,值得推广。Objective To analyze the therapeutic effect of YL-1 needle drainage combined with Urokinase rinsing on treating chronic subdural hematoma.Methods 92 patients with chronic subdural hematoma admitted into the department of neurosurgery in our hospital from March 2012 to May 2016 were selected as research objects.They were divided into two groups including conventional group and experimental group.In the conventional group,simple drilling drainage was used,while in the experimental group,YL-1 needle drainage combined with Urokinase rinsing was adopted.The therapeutic effect in the two groups was compared.Results The total effective rate was 97.83% and 84.78% in the experimental group and the conventional group,respectively（P〈0.05）.The disappearing time of hematoma,rate of residual subdural effusion,and recurrence rate Of hematoma was （7.22±2.12） d,2.17% and 0.00% in the experimental group,which were greatly superior to those in the conventional group （P〈0.05）.Tbere was no significant difference in the score of quality of life （QOL） in the two groups before treatment （P〉0.05）.Afier therapy,the score of QOL in the experimental group was significantly better than that in the conventional group （P〈0.05）.Conclusion Combination of YL-1 needle drainage and Urokinase rinsing obtains a remarkable clinical effect in patients with chronic subdural hematoma and can effectively decrease the recurrence rate of hematoma.At advantages of high operative safety,small trauma and simple and easy in operation,it is beneficial to improve the QOL,and is worthy of practical promotion.

关 键 词：慢性硬膜下血肿 尿激酶 YL-1型针 引流 冲洗 

分 类 号：R651.154[医药卫生—外科学]