小剂量艾司洛尔预先静脉注射减轻高血压冠心病患者气管插管反应的作用分析  

Effect of intravenous injection of small dose of esmolol on alleviating the endotracheal intubation reaction in patients with hypertension and coronary heart disease

作　　者：张玉峰 

机构地区：[1]郑州颐和医院急诊科,河南郑州450047

出　　处：《临床研究》2017年第6期44-45,共2页Clinical Research

摘　　要：目的 研究分析小剂量艾司洛尔预先静脉注射对减轻高血压冠心病患者气管插管反应的作用.方法 选取我院2016年1月至2017年3月在气管插管全麻下进行治疗的82例高血压冠心病患者,将入选患者随机分成研究组与对照组,各41例;其中研究组患者在麻醉前给予小剂量艾司洛尔预注,对照组麻醉前常规给予氯化钠注射液,观察分析患者在不同时间点的平均动脉压（MAP）、心率（HR）以及不良反应情况.结果 全部入选患者的治疗均顺利完成,两组患者插管前的MAP、HR比较,无明显差异（P＞0.05）,而研究组患者插管时、插管后的MAP、HR变化情况均明显优于对照组（P＜0.05）;研究组患者麻醉相关不良反应情况明显优于对照组（P＜0.05）.结论 高血压冠心病患者的全麻手术治疗中,给予小剂量艾司洛尔预注射具有良好的效果,能够将患者插管时的反应明显减轻.Objective To study the effect of intravenous injection of small dose of esmolol on alleviating the endotracheal intubation reaction in patients with hypertension and coronary heart disease. Methods Eighty-two cases of patients with hy- pertension and coronary heart disease treated in our hospital from January 2016 to March 2017 were selected and randomly divided into the research group and control group with 41 cases in each group. The research group was given injection of small dose of esmolol before anesthesia, while the control group was given sodium chloride injection. The mean arterial pres- sure （MAP） and heart rate （HR） at different time points and the adverse reaction incidence were observed and analyzed be- tween two groups. Results There was no significant difference in MAP and HR between the two groups before intubation （P〉 0.05）; the changes of MAP and HR during and after intubation were both significantly better in the research group than those in the control group （P〈0.05）; the adverse reactions of the research group was better than those of the control group （P〈0.05）. Conclusion Before general anesthesia operations in patients with hypertension and coronary heart disease, intravenous injec- tion of small dose of esmolol can get good effect, and effectively alleviate the endotracheal intubation reaction.

关 键 词：高血压冠心病 气管插管反应 艾司洛尔 小剂量 

分 类 号：R614[医药卫生—麻醉学]