超声引导精准治疗获得性免疫缺陷综合征合并肝脓肿的疗效及安全性评价  

Evaluation on efficacy and safety of precise treatment guided by ultrasound for acquired immune deficiency syndrome patients with liver abscess

作　　者：杨学平[1] 张瑶[1] 王连双[1] 王丽萍[1] 

机构地区：[1]首都医科大学附属北京地坛医院超声科,北京100015

出　　处：《中华实验和临床感染病杂志（电子版）》2017年第3期277-281,共5页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

摘　　要：目的探讨超声引导精准治疗获得性免疫缺陷综合征(AIDS)合并肝脓肿的疗效及安全性。方法以2009年1月至2016年4月本院诊治的44例AIDS合并肝脓肿患者为研究对象(共58个脓肿),按照患者脓肿大小分为穿刺抽吸(PA)组与置管引流(PCD)组,比较两组患者术后体温恢复至正常时间、脓腔闭合时间、并发症、一次穿刺治愈率及总治愈率。结果 44个脓肿采用PCD,14个脓肿采用PA,PCD组脓腔闭合时间长于PA组[(18.18±8.73)d vs.(9.14±3.96)d,t=5.353、P<0.001)],PCD组一次穿刺治愈率高于PA组(44/44 vs.8/14,P<0.001),两组患者并发症(0/44 vs.1/14,P=0.241)及体温恢复至正常时间[(1.60±0.52)d vs.(1.36±0.50)d,t=1.543、P=0.128)]差异均无统计学意义;两组总治愈率均为100%;PA组术中脓腔内出血1例;医护人员未发生职业暴露。结论超声引导下精准治疗AIDS合并肝脓肿操作简单、风险低、治愈率高、并发症少。Objective To investigate the efficacy and safety of precise treatment guided by ultrasound for acquired immunodeficiency syndrome （AIDS） patients with liver abscess. Methods Total of 44 AIDS patients with liver abscesses （58 lesions） from January 2009 to April 2016 in our hospital were taken as the research objects, who were divided into percutaneous aspiration （PA） group and percutaneous catheter drainage （PCD） group according the size. The periods of body temperature returned to normal, closure of abscess, cure rate of a puncture, total cure rate and complications were compared between the two groups, respectively. Results There were 44 abscesses treated with PCD and 14 abscesses were treated with PA. The closure period of abscess in PCD group was significantly longer than that in PA group [（18.18 ±8.73） d vs. （9.14 ± 3.96） d; t = 5.353, P 〈 0.001）]. The cure rate of a puncture in PCD group was significantly higher than that in PA group （44/44 vs. 8/14, P 〈 0.001）. Complications （0/44 vs. 1/14, P = 0.241） and period of body temperature returned to normal [（1.60 ± 0.52） d vs. （1.36± 0.50） d; t = 1.543, P = 0.128）] had no significant difference between the two groups, and the total cure rate of each group was 100%. One case with abscesses occured bleeding in PA group. No medical staff was exposed to infection. Conclusions Operation of precise treatment guided by ultrasound for AIDS patients with liver abscess was simple, with lower risk, higher cure rate and less complications.

关 键 词：肝脓肿 超声引导精准治疗 获得性免疫缺陷综合征 

分 类 号：R512.91[医药卫生—内科学]