急性肾损伤病理给我们的启示:器官衰竭的预防  

The enlightenment of histopathology of acute kidney injury: prevention of organ dysfunction

作　　者：谢剑锋[1] 邱海波[1] 

机构地区：[1]东南大学附属中大医院重症医学科,南京210009

出　　处：《中华重症医学电子杂志》2017年第3期166-168,共3页Chinese Journal Of Critical Care & Intensive Care Medicine(Electronic Edition)

基　　金：国家自然基金(81300043;81571874和81601723);江苏省重点学科项目(2017)

摘　　要：急性肾损伤(AKI)是重症医学科常见的临床现象,直接关系到患者预后。临床上急性肾损伤发生往往有一个过程,使其有机会进行预防。此外,即使发展成急性肾损伤,病理学结果也并未发现肾小管细胞坏死,而是出于一种"休眠"状态,提示可通过调控细胞凋亡,细胞周期等策略防止细胞坏死,恢复肾功能。Acute kidney injury （AKI） is very common in intensive care unit （ICU） which is significant associated with the outcome. There is a process to develop to AKI which allows the clinicians make prevention strategy. In addition, the pathology results showed that tubular cells were not necrosis but only in a ＂dormancy＂ status in AKI which indicate that we can prevent necrosis and restore kidney function through regulating the apoptosis and cell cycle.

关 键 词：急性肾功能不全 病理学 预防 

分 类 号：R459.7[医药卫生—急诊医学] R692.5[医药卫生—治疗学]