盐酸氨溴索雾化吸入联合静脉注射治疗新生儿呼吸窘迫综合征的临床效果  

The Clinical Curative Effect of Ambroxol Hydrochloride Aerosol Inhalation Combined with Intravenous Injection in Neonatal Respiratory Distress Syndrome

作　　者：王晓瑜[1] 邓全敏[1] 

机构地区：[1]德阳市人民医院,四川德阳618000

出　　处：《中外医学研究》2017年第21期1-2,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨盐酸氨溴索雾化吸入联合静脉注射治疗新生儿呼吸窘迫综合征的临床效果。方法:选取2014年10月-2016年10月笔者所在医院收治的NRDS患儿84例作为研究对象,按照患儿的出生时间先后将其分为观察组和对照组,每组42例,对照组给予包括盐酸氨溴索雾化治疗在内的常规治疗,而观察组在对照组基础上行盐酸氨溴索静脉注射治疗,比较两组的治疗效果。结果:观察组总有效率(92.86%)显著高于对照组(76.19%),差异有统计学意义(χ~2=4.459,P=0.035)。治疗前,两组新生儿的PaO_2水平比较,差异无统计学意义(P>0.05);治疗后12 h和24 h两组新生儿的PaO_2水平比较,观察组高于对照组,差异均有统计学意义(P<0.05)。结论:采用盐酸氨溴索雾化吸入联合静脉注射治疗NRDS,总有效率显著高于单一盐酸氨溴索雾化吸入,可提升PaO_2水平,促进患儿早日康复。Objective： To explore the clinical curative effect of Ambroxol Hydrochloride aerosol inhalation combined with intravenous injection in neonatal respiratory distress syndrome.Method： 84 cases of NRDS children were selected in our hospital from October 2014 to October 2016.According to child birth time, they were divided into observation group and control group, 42 cases in each group.Control group was given routine therapy including Ambroxol Hydrochloride aerosol inhalation, while based on the control group, the observation group was given Ambroxol Hydrochloride intravenous injection, the treatment effect was compared.Result： The total effective rate in the observation group（92.86%） was significantly higher than the control group（76.19%）, the difference was statistically significant（x2=4.459, P=O.O35）.Before the treatment, two groups of neonatal PaO2 horizontal comparison, there was no statistically significant difference（P〉0.05）; 12 h and 24 h in the two groups after treatment of neonatal PaO2 horizontal comparison, the observation group were higher than the control group, the differences were statistically significant（P〈0.O5）.Conclusion： UsingAmbroxol Hydrochloride aerosolinhalation combined with intravenous injection treatment, total effective rate of NRDS is significantly higher than the single Ambroxol Hydrochloride aerosol inhalation, enhancing the level of PaO2, promoting children recover at an early date.

关 键 词：盐酸氨溴索 雾化吸入 静脉注射 新生儿呼吸窘迫综合征 

分 类 号：R722.1[医药卫生—儿科]