盐酸氨溴索联合糖皮质激素治疗分泌性中耳炎疗效观察  

Efficacy of treatment otitis media with effusion by Ambroxol combined with glucocorticoids

作　　者：侯薇[1] 张铁英[1] 

机构地区：[1]陕西中医药大学附属医院耳鼻喉科

出　　处：《中国生化药物杂志》2017年第7期191-193,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的观察盐酸氨溴索联合糖皮质激素治疗分泌性中耳炎的临床效果。方法选取陕西中医药大学附属医院耳鼻喉科2015年6月~2016年10月收治的分泌性中耳炎患者共81例,按随随机、双盲原则分为观察组42例和对照组39例,对照组给予糖皮质激素治疗,观察组给予盐酸氨溴索联合糖皮质激素治疗,观察比较2组患者治疗前后的纯音听阀测定气导听力水平、听力恢复情况以及临床疗效情况。结果观察组患者治疗后的纯音听阀测定气导听力水平明显高于对照组（P〈0.05）;观察组患者治疗后烟鼓管功能正常比例为85.71%,明显高于对照组48.72%（P〈0.05）;3观察组患者治疗后总有效率为92.86%,明显高于对照组74.36%（P〈0.05）。结论盐酸氨溴索联合糖皮质激素可有效治疗分泌性中耳炎,提高分泌性中耳炎的临床疗效,且易操作,值得临床推广和应用。Objective To observe the clinical results of ambroxol combined with glucocorticoids in the treatment of otitis media with effusion.Methods 81 cases fron June 2015 to 2016 October,were randomly,double-blind principle divided into observation group（ 42cases） and control group（ 39cases）. The control group glucocorticoid therapy observation group were treated with ambroxol combined with glucocorticoid treatment,pure tone was observed before and after treatment were compared listen valve measured air conduction hearing level, hearing recovery and clinical efficacy.Results The observation group were pure tone hearing valve after treatment was measured air conduction hearing level was significantly higher（ P〈 0. 05）; drum pipe tobacco functioning proportion of patients in the observation group after treatment was 85. 71%,significantly higher than 48. 72%（ P〈 0. 05）; The observation group total effective rate was 92. 86%,significantly higher than 74. 36%（ P〈 0. 05）. Conclusion Ambroxol combined with glucocorticoids be effective in treating secretory otitis media,otitis media with effusion improve the clinical efficacy,and easy to operate,and is worthy of clinical application.

关 键 词：盐酸氨溴索 糖皮质激素 分泌性中耳炎 

分 类 号：R764.2[医药卫生—耳鼻咽喉科]