川芎嗪注射液联合尼莫地平治疗原发性开角型青光眼的疗效观察  

Effect of Chuanxiongqin injection combined with nimodipine on primary open angle glaucoma

作　　者：施彦[1] 林鹏耀[1] 陈思明[1] 林呈飞[1] 

机构地区：[1]宁波市第一医院眼科

出　　处：《中国生化药物杂志》2017年第7期334-336,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的观察川芎嗪注射液联合尼莫地平治疗原发性开角型青光眼的疗效。方法我院眼科诊治的112例原发性开角型青光眼患者随机分为2组,各56例。2组均进行尼莫地平常规治疗,观察组另加用川芎嗪注射液,分析其疗效。结果治疗后,观察组视网膜光敏感度、视野缺损、血流量、血流速度、红细胞移动率、视网膜中央动脉PSV、EDV和RI均优于对照组（均P〈0.05）。2组不良反应情况比较差异无统计学意义。结论川芎嗪注射液可改善原发性开角型青光眼视网膜中央动脉和视盘筛板血流状况,改善视网膜光敏感度和视野缺损。Objective To observe the effect of Chuanxiongqin injection combined with nimodipine on primary open angle glaucoma. Methods 112 patients with primary open angle glaucoma in ophthalmology department were grouped two groups,each with 56 cases. Two groups were treated with nimodipine and observation group was treated another with Chuanxiongqin injection to observe effect. Results After treatment,retinal light sensitivity,visual field defect,blood flow,blood flow velocity,erythrocyte migration rate,PSV,EDV and RI in central retinal artery of observation group were better than control group（ P 〈0. 05）. There was no significant difference in adverse reactions between groups. Conclusion Chuanxiongqin injection can improve blood flow status of central retinal artery and optic papillary laminar,retinal light sensitivity and visual field defect for patients with primary open angle glaucoma.

关 键 词：川芎嗪注射液 尼莫地平 原发性开角型青光眼 

分 类 号：R246.82[医药卫生—针灸推拿学]