临床药师参与1例经皮冠状动脉介入术后血小板高反应患者的抗血小板治疗  

Clinical pharmacist's participation on individualized antiplatelet therapy in one patient with high platelet reactivity after percutaneous coronary intervention

作　　者：蒋俊杰[1] 俞吉[2] 王法财[1] 许曼[1] 聂松柳[1] 沈炳香[1] 

机构地区：[1]安徽医科大学附属六安医院药学部,安徽六安237005 [2]淮南市朝阳医院药剂科临床药学室,安徽淮南232001

出　　处：《临床药物治疗杂志》2017年第4期80-84,共5页Clinical Medication Journal

摘　　要：目的:探讨临床药师在个体化抗血小板治疗中的作用。方法:回顾性分析临床药师参与的1例经皮冠状动脉介入术后再发缺血事件的抗血小板治疗的案例。结果:临床药师通过患者的疾病、基因型、药物相关作用等因素从药学角度分析再发缺血事件的原因,并参与药物治疗和药学监护,协助临床医生为患者制定个体化抗血小板治疗方案。结论:利用基因检测技术,临床药师为患者实施个体化抗血小板治疗,保障患者用药的安全、有效。Objective： To evaluate the role of clinical pharmacists in individualized antiplatelet therapy. Methods： The process of the participation of one clinical pharmacist in individualized antiplatelet therapy in one patient with ischemic events after percutaneous coronary intervention （PCI） was retrospectively analyzed. Results： The clinical pharmacist analyzed the causes of the ischemic events after PC! from the perspective of disease, genotype, drug interactions, etc, and took part in the drug treatment and pharmaceutical care to provide individualized antiplatelet therapy. Conclusion： Clinical pharmacists can implement individualized antiplatelet therapy by gene detection to ensure the safety and effectiveness of drug use.

关 键 词：经皮冠状动脉介入术 缺血事件 氯吡格雷抵抗 基因多态性 血小板高反应性 临床药师 

分 类 号：R969.3[医药卫生—药理学]