家庭运动干预联合饮食控制对妊娠期糖尿病患者脂肪因子及妊娠结局的影响  

Effect of family exercise intervention combined with diet control on adipocytokines and pregnancy outcomes in patients with gestational diabetes mellitus

作　　者：刘小英[1] 刘红梅[1] 谯艳[1] 漆小玲[1] 叶文春[1] 方向明[1] 刘云[1] LIU Xiao-Ying LIU Hong-Mei QIAO Yan et al(Department of Endocrinology, Mianyang Municipal Central Hospital, Mianyang , Sichuan 621000, China)

机构地区：[1]绵阳市中心医院内分泌科,四川绵阳621000

出　　处：《中国妇幼保健》2017年第14期3114-3117,共4页Maternal and Child Health Care of China

基　　金：2015年四川省卫生和计划生育委员会课题(150086)

摘　　要：目的探究家庭运动干预联合饮食控制对妊娠期糖尿病患者脂肪因子及妊娠结局的影响。方法选取2015年5月-2016年5月该院收治的89例妊娠期糖尿病患者作为研究对象,采用随机数字表法将患者分为观察组(43例)和对照组(46例),对照组仅予常规宣传教育与护理。观察组在对照组基础上行家庭运动干预联合饮食控制,比较并分析两组患者干预前后的血糖水平、血脂及脂肪因子水平和妊娠结局。结果干预后,观察组空腹血糖、餐后2 h血糖均低于对照组,胰岛素敏感指数高于对照组(P<0.05);观察组甘油三酯(TG)、血清总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、肿瘤坏死因子(TNF-α)及瘦蛋白(leptin)均显著低于对照组,差异具有统计学意义(P<0.05)。观察组妊娠期高血压疾病、早产、剖宫产、产后出血、产褥感染、新生儿窒息和新生儿低血糖的发生率均显著低于对照组(P<0.05)。结论家庭运动干预联合饮食控制能够显著降低患者血糖水平,调控血脂及脂肪因子水平,改善妊娠结局。Objective To explore the effect of family exercise intervention combined with diet control on adipocytokines and pregnancy outcomes in patients with gestational diabetes mellitus（ GDM）. Methods A total of 89 GDM patients were selected from the hospital from May 2015 to May 2016 as research object,then they were divided into observation group（ 43 cases） and control group（ 46 cases） by random number table,the patients in control group only received routine education and nursing care,and the patients in observation group were additionally given family exercise intervention combined with diet therapy on the basis of routine education and nursing care. The levels of blood glucose,blood lipids,adipocytokines,and pregnancy outcomes in the two groups were compared and analyzed. Results After intervention,the fasting blood glucose and postprandial 2-hour blood glucose in observation group were statistically significantly lower than those in control group,and insulin sensitivity index in observation group was statistically higher than that in control group（ P〈0. 05）. The levels of triglyceride（ TG）,serum cholesterol（ TC）,high-density lipoprotein cholesterol（ HDL-C）,low-density lipoprotein cholesterol（ LDL-C）,tumor necrosis factor-α（ TNF-α）,and leptin in observation group were statistically significantly lower than those in control group（ P〈0. 05）. The incidence rates of hypertensive disorder complicating pregnancy,premature delivery,cesarean section,postpartum hemorrhage,puerperal infection,neonatal asphyxia,and neonatal hypoglycemia in observation group were statistically significantly lower than those in control group（ P〈0. 05）. Conclusion Family exercise intervention combined with diet control can significantly reduce the levels of blood glucose,regulate the levels of blood lipids and adipocytokines,and improve pregnancy outcomes.

关 键 词：运动与饮食干预 妊娠期糖尿病 脂肪因子 妊娠结局 

分 类 号：R714.256[医药卫生—妇产科学]