口腔干燥综合征常见证候及证候要素文献与临床研究  

Literature Research and Clinical Investigation on Common Syndromes and Syndrome Factors of Xerostomia

作　　者：丁洋[1,2] 韩建民[3] 陶琳[1] 刘赓[1] 沈晨[1] 孟梦[1] 侯亚男[1] 张声生[1] 

机构地区：[1]首都医科大学附属北京中医医院消化中心,北京100010 [2]北京中医药大学东直门医院,北京100700 [3]北京大学口腔医院,北京100081

出　　处：《世界中医药》2017年第4期929-932,共4页World Chinese Medicine

基　　金：北京市自然科学基金项目(编号:7164265)--调肝理脾方治疗口腔干燥综合征的机制研究;国家自然科学基金项目(编号:81400560)--丹参和麦门冬促唾液分泌的机制及在义齿黏附剂中的缓释调控

摘　　要：目的:探讨中医文献及临床调查口腔干燥综合征证候及其证候要素分布特点。方法:通过检索文献,选取2000—2015年有关口腔干燥综合征中医辨证文献,建立Epidata2.0数据库,应用SPSS 17.0进行描述性统计分析。结果:在文献研究方面,有关口腔干燥综合征出现频率大于10%的常见证候类型依次为:肺阴不足、胃阴不足、阴虚火旺、肝肾阴虚、肾阴不足;出现频率≥5%的病位类证候要素分别为:肺、肾;≥5%的病性类证候要素为:阴虚、火。临床调查方面,出现频率大于10%的常见证后类型依次为:肺阴不足、气阴两虚、胃阴不足、肝肾阴虚;出现频率≥5%的病位类证候要素分别为:肺;≥5%的病性类证候要素为:阴虚、火。结论:口腔干燥综合征的辨证分型复杂多样,证候要素相对简约,对临床辨证论治起到执简驭繁的作用。Objective：To analyze the distribution characteristics of common syndromes and syndrome factors of xerostomia in literature researches and clinical investigations.Methods：Through selecting TCM literature about the syndrome differentiation of xerostomia from 2000-2015, build Epidata 2.0 database and use SPSS 17.0 to make descriptive statistical analysis.Results：In the aspect of literature research, the occurrence frequency of the following syndromes of xerostomia are higher than 10%：lung-yin deficiency, stomach-yin deficiency, yin deficiency with effulgent fire, liver-kidney yin deficiency, kidney-yin deficiency.The disease locations whose occurrences frequency are higher than 5% are lung and kidney.The disease nature whose occurrence frequency are higher than 5% are yin deficiency and fire.In the aspect of clinical investigation, the occurrence frequency of the following syndromes are higher than 10%：lung-yin deficiency, qi-yin deficiency, stomach-yin deficiency, liver-kidney yin deficiency.The disease location whose occurrence frequency is higher than 5% is lung.The disease nature whose occurrence frequency are higher than 5% are yin deficiency and fire.Conclusion：Although there are a great number of syndromes when it comes to xerostomia, the syndrome factors of the disease are not complicated, which exerts positive influence on the syndrome differentiation in clinical practice.

关 键 词：口腔干燥综合征 证候 证候要素 文献分析 临床调查 

分 类 号：R241.6[医药卫生—中医诊断学]