中西医结合治疗溃疡性结肠炎的临床研究  

Clinical Study of Yunnan Hongyao Capsule in the Treatment of Ulcerative Colitis

作　　者：左振魁[1] 韩佳瑞[2] 

机构地区：[1]河南省中医院肛肠科,郑州450002 [2]河南省中医院肾病科,郑州450002

出　　处：《世界中医药》2017年第6期1347-1349,1353,共4页World Chinese Medicine

基　　金：国家自然科学基金项目(编号:30772801)--结肠粘膜中性粒细胞凋亡延迟机制及清肠栓调控作用

摘　　要：目的:观察云南红药胶囊治疗溃疡性结肠炎的临床疗效。方法:采用随机对照研究方法,60例溃疡性结肠炎患者随机分为治疗组及对照组,分别给予云南红药胶囊联合美沙拉嗪缓释颗粒剂口服及单独应用美沙拉嗪缓释颗粒剂,疗程4周。结果:云南红药胶囊可明显改善溃疡性结肠炎患者腹痛、腹泻、黏液脓血便、里急后重等临床症状,减少患者大便常规红细胞及白细胞,减轻患者肠黏膜损伤,总有效率90%,与单独口服美沙拉嗪缓释颗粒剂比较有统计学意义。结论:云南红药胶囊治疗溃疡性结肠炎,疗效满意,无严重不良反应,值得临床推广。Objective： To observe the clinical efficacy of Yunnan Hougyao capsule in the treatment of ulcerative colitis. Methods： Using randomized study method,60 cases of ulcerative colitis were randomly divided into treatment group and control group,were given Yunnan Hongyao capsule combined with the beauty of salad and glipizide sustained-release granule oral sustained-release granules of salad for 4 weeks. Results ： Yunnan Hongyao capsule can obviously improve the patients with ulcerative colitis with ab- dominal pain, diarrhea, bloody purulent ＂stool, tenesmus and other clinical symptoms, reduce patient stool red blood cells and white blood cells, reduce intestinal mucosal injury, the total efficiency of 90% , there was significant difference compared with the single oral beauty of salad sustained-release granule. Conclusion： The effect of Yunnan Hongyao capsule in the treatment of ulcerative colitis, with no serious adverse reactions,it is worthy of clinical promotion.

关 键 词：溃疡性结肠炎 云南红药胶囊 中西医结合疗法 

分 类 号：R856.2[医药卫生—航空、航天与航海医学] R574.1[医药卫生—临床医学]