两种不同类型新生儿败血症的相关危险因素  

Related risk factors for two different types of neonatal sepsis

作　　者：崔婷婷 

机构地区：[1]山东省莱芜市妇幼保健院,271199

出　　处：《中国实用医药》2017年第18期19-20,共2页China Practical Medicine

摘　　要：目的研究早发型败血症与晚发型败血症新生儿败血症的相关危险因素。方法 98例败血症新生儿根据败血症类型分为早发型组(早发型败血症患儿48例)与晚发型组(晚发型败血症患儿50例),对两组患儿的新生儿室息、胎膜早破、肺部感染、脐部感染、羊水污染、喂养不当以及出生体重较低等败血症相关指标进行比较。结果早发型组新生儿室息、胎膜早破、肺部感染、羊水污染发生率分别为33.33%、16.67%、68.75%、41.67%,明显高于晚发型组的14.00%、20.00%、38.00%、12.00%,差异均具有统计学意义(P<0.05);晚发型组脐部感染、喂养不当、出生体重较低发生率分别为34.00%、72.00%、42.00%,明显高于早发型组的10.42%、35.42%、22.92%,差异均具有统计学意义(P<0.05)。经过Logistic回归分析显示,发生新生儿室息、胎膜早破、肺部感染、羊水污染对于早发型败血症存在较大影响;发生脐部感染、喂养不当、出生体重较低对于晚发型败血症存在较大影响。结论新生儿患儿出现早发型败血症的相关危险因素有新生儿室息、胎膜早破、新生儿肺部感染以及羊水污染;出现晚发型败血症的相关危险因素有出生体重较低、新生儿脐部感染以及喂养不当。因此要给予一定的预防措施,并且在实际的新生儿败血症治疗中要根据其不同病情的类型进行相关治疗,且需仔细探究其危险因素,以便有效的降低新生儿败血症病例。Objective To research related risk factors for neonatal early-onset sepsis and late-onset sepsis. Methods A total of 98 newborn with sepsis were divided by their different types into early-onset group（48 cases with early-onset sepsis） and late-onset group（50 cases with late-onset sepsis）. Comparison was made on sepsis-related indexes, such as neonatal asphyxia, premature rupture of fetal membranes, pulmonary infection, navel infection, amniotic fluid pollution, improper feeding, and low birth weight, between the two groups. Results The early-onset group had incidence of neonatal asphyxia, premature rupture of fetal membranes, pulmonary infection, and amniotic fluid pollution respectively as 33.33%, 16.67%, 68.75% and 41.67%, which were all much higher than 14.00%, 20.00%, 38.00% and 12.00% in the late-onset group, and their differences all had statistical significance（P〈0.05）. The late-onset group had incidence of navel infection, improper feeding, and low birth weight respectively as 34.00%, 72.00% and 42.00%, which were all higher than 10.42%, 35.42%, 22.92% in the early-onset group, and their differences all had statistical significance（P〈0.05）. Logistic regression analysis showed large impact by neonatal asphyxia, premature rupture of fetal membranes, pulmonary infection, and amniotic fluid pollution on early-onset sepsis, and navel infection, improper feeding, and low birth weight on late-onset sepsis. Conclusion Related risk factors for neonatal early-onset sepsis include neonatal asphyxia, premature rupture of fetal membranes, pulmonary infection, and amniotic fluid pollution, and those for late-onset sepsis were navel infection, improper feeding, and low birth weight. Certain prevention measures are necessary in treatment, while related therapy in accordance with various disease condition is essential for neonatal sepsis treatment. Detailed investigation of risk factors can effectively reduce newborn with sepsis.

关 键 词：不同类型 早发型败血症 患儿 晚发型败血症 相关危险因素 

分 类 号：R722.131[医药卫生—儿科]