寒邪致病对大鼠血糖、胰岛素水平的影响  

Effects of pathogenic cold pathogen on blood glucose and insulin levels in rats

作　　者：杨宇琦[1] 杨泽武[1] 秦伟[1] 严宪才[1] 王米渠[2] 

机构地区：[1]广州中医药大学附属中山医院,广东中山528400 [2]成都中医药大学基础医学院,成都610000

出　　处：《吉林中医药》2017年第7期708-710,共3页Jilin Journal of Chinese Medicine

基　　金：广东省中山市科技局项目(2014A1FC178)

摘　　要：目的初步探讨寒邪致病对大鼠血糖、胰岛素水平的影响。方法模拟寒邪致病环境下,同时将A组大鼠于常温下正常喂养4周、B组大鼠每天置于4℃左右环境下喂养约5 h连续4周后,观察2组大鼠的血糖与胰岛素水平变化。血糖测定使用电子血糖分析仪,胰岛素测定采用采用ELISA法。结果模拟寒邪致病环境下喂养4周后的B组大鼠血糖及胰岛素水平均出现升高,同正常A组大鼠比较差异有统计学意义(P<0.01)。结论大鼠受寒邪影响后出现血糖和胰岛素升高,提示寒邪致病对大鼠的血糖、胰岛素水平存在影响。Objective Preliminary study on the effect of cold pathogen factors on blood glucose and insulin levels of rats. Methods Simulated pathogenic environment of pathogenic cold, the rats of A group were fed at normal temperature for 4 weeks. Rats in group B were fed about 5 h in 4 ℃ for 4 weeks. The changes of blood glucose and insulin levels were observed in two groups of rats. Blood glucose was measured with an electronic blood glucose analyzer, and insulin was measured by ELISA. Results The blood glucose and insulin levels were increased in the B group after feeding 4 weeks. Compared with A group, the difference was significant（P〈0.01）. Conclusion Effects of elevated blood glucose and insulin in rats after cold evil. The experiment indicated that the blood glucose and insulin level were affected by cold pathogen in rats.

关 键 词：寒邪致病 血糖 胰岛素 

分 类 号：R587.1[医药卫生—内分泌]