河北省某矿业集团煤矿工人血红蛋白与代谢综合征及其组分相关性分析  

Correlation analysis on hemoglobin and metabolic syndrome and its components among coal miners in a mining company in Hebei

作　　者：尚红光[1] 卫俊峰[1] 王爱珉[2] 孙永峰[1] 

机构地区：[1]冀中能源峰峰集团有限公司职业病防治院健康管理中心,河北邯郸056201 [2]冀中能源峰峰集团有限公司总医院检验科,河北邯郸056200

出　　处：《职业与健康》2017年第11期1478-1481,共4页Occupation and Health

摘　　要：目的探讨煤矿工人血红蛋白水平与代谢综合征(MS)及其组分(血压、血脂、血糖、肥胖)的相关性。方法以河北省某矿业集团在岗职业健康检查人群为研究对象。按血红蛋白(Hb)水平四分位数分为4组,以SPSS 17.0统计软件分析其Hb水平与收缩压(SBP)、舒张压(DBP)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、空腹血糖(FPG)、体质指数(BMI)之间的相关性。结果煤矿工人MS患病率17.73%,MS组Hb[(150.26±11.12)g/L],显著高于非MS组Hb[(144.64±12.35)g/L],差异有统计学意义(P<0.01),不同Hb的水平与年龄、SBP、DBP、TC、TG、HDL-C、FPG、BMI比较,差异均有统计学意义(均P<0.01),Hb最低四分位组到最高四分位组,随着Hb水平的上升,SBP、DBP、TC、TG、FPG、BMI各指标水平升高,HDL-C水平降低。通过Pearson分析,研究对象的Hb与TG、TC、FPG、SBP、DBP、BMI等均呈显著正相关(r值分别为0.209、0.165、0.144、0.237、0.218、0.127,均P<0.01),与HDL-C呈负相关(r值为-0.175,P<0.01)。多因素逐步回归分析后显示,Hb的升高与MS发病风险的增加呈正相关(β=0.123、0.185、0.122、0.130、-0.204、0.104)。结论煤矿工人Hb与MS及血压、血脂、血糖、BMI存在相关性,可为该人群MS的早期诊断提供参考。[Objective] To explore the correlation on hemoglobin and metabolic syndrome（MS） and its components（blood pressure,blood lipid,blood glucose,fat） among coal miners.[Methods]The on-guard workers who took health examination were selected as study objects and divided into four groups by quartile of Hb. The correlations of Hb levels with systolic blood pressure（SBP）,diastolic blood pressure（DBP）,triglyceride（TG）,total cholesterol（TC）,high density lipoprotein cholesterol（HDL-C）,fasting plasma glucose（FPG） and body mass index（BMI） were analyzed by SPSS 17.0.[Results]The prevalence rate of MS among coal miners was 17.73%,The level of Hb in MS group [（150.26 ±11.12） g/L] was higher than that in non-MS group[（144.64±12.35）g/L],the difference was statistically significant（P0.01）. The differences of age,SBP,DBP,TC,TG,HDL-C,FPG and BMI in different Hb level group were statistically significant（all P0.01）. With the increasing of Hb levels,the levels of SBP,DBP,TC,TG,FPG,and BMI increased,ant the level of HDL-C decreased. By Pearson analysis,the Hb level was positively correlated with levels of SBP,DBP,TC,TG,FPG,and BMI（r=0.209,0.165,0.144,0.237,0.218,0.127,all P0.01）,and negatively correlated with HDL-C（r =-0.175,P 0.01）. Multiple stepwise regression analysis showed that the increasing of Hb level was positively correlated with increased risk of MS（β=0.123,0.185,0.122,0.130,-0.204,0.104）.[Conclusion]There are correlations of Hb with MS and blood pressure,blood lipid,blood glucose and BMI among coal miners,which can provide reference for early diagnosis of MS.

关 键 词：血红蛋白 代谢综合征 血压 血脂 空腹血糖 煤矿工人 

分 类 号：R181.31[医药卫生—流行病学]