联合胎盘多肽注射液治疗初治菌阳肺结核患者的疗效观察  

Clinical observation of curative effect of placenta polypeptide injection therapy for initial-treated positive pulmonary tuberculosis

作　　者：孙德斌[1] 

机构地区：[1]沈阳市胸科医院,辽宁沈阳110000

出　　处：《临床肺科杂志》2017年第9期1652-1655,共4页Journal of Clinical Pulmonary Medicine

摘　　要：目的观察初治菌阳肺结核行联合胎盘多肽注射液治疗的疗效。方法选取我院收治128例初治菌阳肺结核活动期患者临床资料,按治疗方式不同分为两组,各64例,对照组行常规抗结核药治疗,观察组在其基础上结合胎盘多肽注射液,比较两组临床疗效。结果观察组治疗后痰涂片转阴率、肺部空洞关闭率、病灶吸收率均比对照组高(P<0.05);观察组治疗后咳嗽、胸闷、喀痰等症状缓解时间均比对照组短(P<0.05);观察组治疗后复发率比对照组低,3个月后各项免疫功能指标均优于对照组(P<0.05)。结论初治菌阳肺结核采用胎盘多肽注射液及抗结核药联合治疗可提高痰涂片转阴率,改善临床症状,且免疫功能提高,远期复发率低。Objective To observe the curative effect of placenta polypeptide injection therapy for initial-treated positive pulmonary tuberculosis. Methods The clinical data of 128 cases of initial-treated positive pulmonary tuberculosis patients were collected,and they were randomly divided into two groups,64 cases in each group. The control group was given routine anti-tuberculosis medicine treatment,and the observation group was additionally treated with placenta polypeptide injection. Their clinical curative effect was compared. Results Their sputum smear negative conversion rate,pulmonary cavity closure rate,and lesion absorption rate were higher in the observation group than in the control group( P < 0. 05). After treatment,the symptom relieving time such as cough,chest distress and sputum was shorter in the observation group than in the control group( P < 0. 05). The recurrence rate was lower in the observation group than in the control group,and the immune function indexes were better in the observation group than in the control group( P < 0. 05). Conclusion Placenta polypeptide injection combined with anti-TB drugs can increase the sputum smear negative conversion rate,improve the clinical symptoms,and enhance immune function in treatment of initial-treated positive pulmonary tuberculosis,with low long-term recurrence rate.

关 键 词：胎盘多肽 肺结核 活动期 不良事件 复发 

分 类 号：R521[医药卫生—内科学]