Heavy Metal Assessment among Chinese Nonferrous Metal-exposed Workers from the Jinchang Cohort Study  

作　　者：YANG Ai Min CHENG Zhi Yuan PU Hong Quan CHENG Ning LI Hai Yan LIU Si Min DING Jiao LI Juan Sheng HU Xiao Bin REN Xiao Wei ZHENG Tong Zhang BAI Ya Na 

机构地区：[1]Institute of Epidemiology and Statistics, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China [2]Department of Epidemiology, School of Public Health, Brown University, Providence, RI 02906, USA [3]Evidence-Based Medicine Center and Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, College of Basic Medicine, Lanzhou University, Lanzhou 730000, Gansu, China [4]Workers' Hospital of Jinchuan Group Co., Ltd., Jinchang 737100, Gansu, China [5]Center of Medical Laboratory of Basic Medicine College, Lanzhou University, Lanzhou 730000, Gansu, China

出　　处：《Biomedical and Environmental Sciences》2017年第7期530-534,共5页生物医学与环境科学（英文版）

基　　金：supported by Project of Employees Health Status and Disease Burden Trend Study in Jinchua Nonferrous Metals Corporation,Grant JKB20120013;Fogarty training grants D43TW 008323;and D43TW 007864-01 from the US National Institutes of Health

摘　　要：Environmental exposure to heavy metals has been linked to a wide range of human health hazards. We detected the levels of 15 metals in urine samples from 500 representative sub-samples in an ongoing occupational cohort study （Jinchang Cohort） to directly evaluate metal exposure levels. Fifteen metals, namely As, Ba, Be, Cd, Cs, Cr, Co, Cu, Pb, Mn, Ni, Se, TI, U, and Zn, were detected by inductively coupled plasma quadruple mass spectrometry. The results showed that median creatinine adjustment and geometric mean urinary metal levels were higher in the heavy metal-exposed group, except Se and Zn, than other reported general or occupational populations. Further studies should address the effects of heavy metals on human health.Environmental exposure to heavy metals has been linked to a wide range of human health hazards. We detected the levels of 15 metals in urine samples from 500 representative sub-samples in an ongoing occupational cohort study （Jinchang Cohort） to directly evaluate metal exposure levels. Fifteen metals, namely As, Ba, Be, Cd, Cs, Cr, Co, Cu, Pb, Mn, Ni, Se, TI, U, and Zn, were detected by inductively coupled plasma quadruple mass spectrometry. The results showed that median creatinine adjustment and geometric mean urinary metal levels were higher in the heavy metal-exposed group, except Se and Zn, than other reported general or occupational populations. Further studies should address the effects of heavy metals on human health.

关 键 词：from Co high As that of were Heavy Metal Assessment among Chinese Nonferrous Metal-exposed Workers from the Jinchang Cohort Study than 

分 类 号：R135[医药卫生—劳动卫生]