胎儿透明隔腔异常的产前超声诊断及其临床意义分析  

Prenatal ultrasonic diagnosis of fetal cavum septum pellucidum abnormalities and its clinical significance

作　　者：尤淑艳[1] 荆春丽[1] 张鹏[1] YOU Shuyan JING Chunli ZHANG Peng(Department of Ultrasound, Dalian Maternity and Child Health Care Hospital, Dalian 116033, China)

机构地区：[1]大连医科大学附属大连妇产医院大连市妇幼保健院超声科,辽宁省大连市116033

出　　处：《临床超声医学杂志》2017年第7期487-490,共4页Journal of Clinical Ultrasound in Medicine

摘　　要：目的探讨产前超声诊断胎儿透明隔腔异常的临床意义。方法选取经我院产前超声诊断为胎儿透明隔腔异常的孕妇88例,总结分析其合并畸形的超声特征及随访结果。结果 88例透明隔腔异常胎儿中,透明隔腔增大9例,其中合并韦氏腔存在8例,伴发侧脑室轻度扩张1例;透明隔腔缩小12例,其中胼胝体发育不良1例,合并脑积水2例;透明隔腔缺如67例,其中孤立性透明隔腔缺如5例,合并其他中枢神经系统异常62例,包括胼胝体发育不良22例,前脑无裂畸形16例,Dandy-Walker畸形8例,Arnold-ChiariⅡ畸形3例,脑积水6例,视-隔发育不良2例,蛛网膜囊肿2例,侧脑室轻度扩张3例。88例透明隔腔异常胎儿随访结果:73例胎儿引产或出生后证实与产前超声诊断一致,2例误诊,13例失访。结论产前超声检出胎儿透明隔腔异常是诊断胎儿颅内结构异常的一个重要线索,对判断胎儿中枢神经系统畸形有重要临床意义。Objective To investigate the clinical significance of prenatal ultrasound in diagnosis of fetal cavum septum pellucidum（CSP）abnormalities.Methods Eighty-eight cases of fetal CSP abnormalities diagnosed by prenatal ultrasound in our hospital were retrospectively analyzed,and the ultrasonic features and follow-up results were summarized.Results Eighty-eight cases of fetal CSP abnormalities included：9 cases with enlarged CSP,12 cases with reduction of CSP,67 cases with absence of CSP.In 9 cases of enlarged CSP,1 case was complicated with mild ventriculomegaly,8 cases with cavum vergae.In the 12 cases of CSP reduction,1 case was complicated with callosal agenesis,2 cases with hydrocephalus.In 67 cases of CSP absence,5 cases were simple CSP absence,62 cases were combined with other central nervous system abnormalities,including 22 cases with callosal agenesis,16 cases with holoprosencephaly,8 cases with Dandy-Walker,3 cases with Arnold Chiari Ⅱ,6 cases with hydrocephalus,2 cases with Spto-optic dysplasia,2 cases with arachnoid cyst,3 cases with mild ventriculomegaly.Eighty-eight cases of abnormal fetal CSP were followed up：73 cases of fetal induction or after birth were confirmed to be consistent with prenatal ultrasound diagnosis,2 cases were misdiagnosed,13 cases were lost to follow-up.Conclusion Prenatal ultrasound detection of fetal CSP abnormalities is an important clue to the diagnosis of fetal intracranial structural abnormalities,which has an important clinical significance to determine the fetal central nervous system.

关 键 词：超声检查 透明隔腔 中枢神经系统畸形 

分 类 号：R714.5[医药卫生—妇产科学] R445.1[医药卫生—临床医学]