孕晚期不同引产方法的临床应用效果比较  

Comparison of clinical application effects with different methods of induction of labor in late pregnancy

作　　者：薛娟[1] 王月兰[1] 李幼娟[1] 王娜[1] 王丽秀[1] 夏丰娜 王君朴 

机构地区：[1]河北省第七人民医院产科,河北定州073000

出　　处：《中国医药导报》2017年第21期121-124,共4页China Medical Herald

基　　金：河北省医学科学研究重点课题计划项目(20150091)

摘　　要：目的探讨Foley尿管低位小水囊、小剂量米索前列醇阴道后穹隆给药和小剂量缩宫素静脉滴注在孕晚期妊娠促宫颈成熟和引产中的应用效果。方法选取2014年4月~2016年1月于河北省第七人民医院住院的180例孕晚期初产妇作为研究对象,随机分成水囊组、米索前列醇组和缩宫素组,各60例,分别给予Foley尿管小水囊置入宫颈内口引产、小剂量米索前列醇阴道后穹隆给药引产和小剂量缩宫素静脉滴注引产。观察三组的促宫颈成熟和引产效果、分娩结局以及新生儿出生情况。结果水囊组和米索前列醇组用药后的宫颈Bishop评分均显著高于缩宫素组,差异有统计学意义(P<0.05);水囊组和米索前列醇组引产总有效率均显著高于缩宫素组,差异有统计学意义(P<0.05);水囊组和米索前列醇组的引产至临产时间和总产程均短于缩宫素组,差异有统计学意义(P<0.05);水囊组和米索前列醇组阴道分娩率显著高于缩宫素组,剖宫产率显著低于缩宫素组,差异有统计学意义(P<0.05);三组产后出血量、新生儿体重、羊水污染以及新生儿窒息发生率比较,差异无统计学意义(P>0.05)。结论 Foley尿管低位小水囊和小剂量米索前列醇阴道后穹隆给药用于孕晚期妊娠产妇引产中均具有良好的促宫颈成熟作用,可提高引产成功率,降低剖宫产率,安全有效,值得临床应用。Objective To discuss application effects with low small bladders, small dose of Misoprostol after vaginal fornix and small dose of Oxytocin intravenous drip for induced labor of late pregnancy. Methods 180 late pregnant women from April 2014 to January 2016 were selected and randomly divided into 60 patients of them accepted with foley catheter low water bladders for induced labor were taken as water bladders group, 60 patients of them accepted with small dose of Misoprostol after vaginal fornix for induced labor were taken as Misoprostol group, and another 60 patients of them accepted with small dose of Oxytocin intravenous drip for induced labor were taken as Oxytocin group.The effect of cervical ripening and induced labor, delivery outcome and birth state of newborns among three groups were observed. Results Bishop scores in water bladders group and Misoprostol group after interventions were higher than those in Oxytocin group, the differences were statistically significance（P〈0.05）. Ttotal effective rate of induced labour in water bladders group and Misoprostol group were higher than those in Oxytocin group, the differences were statistically significant（P〈0.05）. Induction of labor to labor time and total labor in water bladders group and Misoprostol group were shorter than those in Oxytocin group, the differences were statistically significant（P〈0.05）. Vaginal delivery rates in water bladders group and Misoprostol group were higher than those in Oxytocin group, cesarean section rate in water bladders group and Misoprostol group were lower than those in Oxytocin group, the differences were statistically significant（P〈0.05）. The amount of postpartum hemorrhage, newborn′s weight, amniotic fluid contamination and newborn asphyxia rate among three groups were compared, with no statistical difference（P〈0.05）. Conclusion Foley catheter low water bladders and small dose of Misoprostol after vaginal fornix apply to induce labor of late pregnancy with effects of cervical ripening that c

关 键 词：低位水囊 米索前列醇 促宫颈成熟 引产 

分 类 号：R714.21[医药卫生—妇产科学]