中药黄酮类成分提取工艺研究进展  

Research Advances in Extraction Flavonoids from Chinese Medicinal Herbs

作　　者：贺敬霞 牟倩倩 杨滨[1] 尹蓉莉[2] 李化[1] He Jingxia Mou Qianqian Yang Bin Yin Rongli Li Hua(State Key Laboratory Breeding Base of Dao-di Herbs Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China Chengdu College of TCM,Chengdu 611137,China)

机构地区：[1]中国中医科学院中药研究所道地药材国家重点实验培育基地,北京100700 [2]成都中医药大学药学院,四川成都611137

出　　处：《亚太传统医药》2017年第15期30-36,共7页Asia-Pacific Traditional Medicine

基　　金：国家自然科学基金项目(81202903;81573534);国家中医药管理局中医药行业科研专项(201407003)

摘　　要：黄酮类化合物是植物体内的次生代谢产物,在治疗高血压、糖尿病、动脉粥样硬化等疾病上有显著疗效。天然黄酮类化合物母核上常含有羟基、甲氧基、烃氧基、异戊烯氧基等不同的取代基,其理化性质也存在显著差异,因而不同的提取工艺会影响到中药黄酮的提取效率,进而影响到临床药效的发挥。为此,对近10年关于不同类型的黄酮类成分提取的文献进行梳理,比较分析各种方法的优缺点,试图找到适合不同类型黄酮类成分特点的高效简便、经济环保的提取方法,为天然黄酮类资源进一步的开发与利用提供有益参考。Flavonoids are secondary metabolites in plants, which have obvious treatments in hypertension, diabetes, atherosclerosis and so on. Natural flavone nucleus often contain different substituents, including hydroxyl, methoxy, alkoxy, and isopentenyl oxy, which result in different physicochemical properties. So, different extraction methods will affect the extraction efficiency of flavonoids and their clinical efficacy. Therefore,this paper collected the literature on the extraction of different types of flavonoids in the last 10 years, compared the advantages and disadvantages of various methods, and tried to find some efficient, simple, economical and environ- mentally friendly methods for extracting different types of flavonoids. Also, this paper provide a useful reference for further develo- ping the natural flavonoid resoures. ：

关 键 词：黄酮类成分 提取工艺 研究进展 

分 类 号：R284.2[医药卫生—中药学]