不同民族心力衰竭患者间N端脑钠肽前体对比分析  

Comparative Analysis of N-terminal Pro-brain Natriuretic Peptide in Patients With Different Ethnic Heart Failure

作　　者：高勇[1] 郝洁[2] 柏晓莉 张红[1] 

机构地区：[1]新疆生产建设兵团第九师医院内一科,新疆额敏834601 [2]新疆生产建设兵团第九师医院医教处,新疆额敏834601

出　　处：《中国继续医学教育》2017年第16期54-55,共2页China Continuing Medical Education

摘　　要：目的研究汉族和哈萨克族心力衰竭患者N端脑钠肽前体(NT-probnp)水平。方法选取2014年10月—2015年6月我院收治的慢性心力衰竭II^IV患者共67例,汉族32例、哈萨克族35例。对所有患者的症状体征、心电图和超声心动图、NT-proBNP、心功能分级等资料进行多因素回归分析。结果 NYHA心功能分级、性别、左室舒张末期内径是NT-proBNP独立预测因素。结论对于已经出现失代偿心力衰竭的患者,不同种族心力衰竭患者NT-proBNP水平无差异,可建立统一心力衰竭NT-proBNP诊断标准。Objective To study the level of NT-probnp in Han and Kazak heart failure patients. Methods A total of 67 patients with chronic heart failure II to IV in our hospital from October 2014 to June 2015 were enrolled with Han nationality 32 cases, Kazak 35 cases. Symptoms, signs, electrocardiogram, echocardiography, NT-proBNP, cardiac function classification and other data of all patients were analyzed using multivariate regression analysis. Results NYHA cardiac function grade, sex, left ventricular end diastolic diameter was independent predictor of NTproBNP. Conclusion NT-proBNP was not significantly different in patients with decompensated heart failure. NT-proBNP diagnostic criteria could be established for patients with different heart failure.

关 键 词：N端脑钠肽前体 心力衰竭 左室舒张末期内径 脑钠肽 

分 类 号：R541[医药卫生—心血管疾病]