膝周痛点射频热凝治疗膝关节骨性关节炎疼痛的临床观察  

CLINICAL OBSERVATION OF GENICULAR NERVE RADIOFREQUENCY ABLATION ON TREATMENT OF REFRACTORY KNEE OSTEOARTHRITIC PAIN

作　　者：杨文荣[1,2] 艾登斌[2] 谢平[2] 王英[2] 付世欧[2] 

机构地区：[1]青岛大学药学院,青岛266021 [2]青岛市市立医院疼痛科青岛市疼痛临床研究治疗中心,青岛266011

出　　处：《中国疼痛医学杂志》2017年第7期515-517,523,共4页Chinese Journal of Pain Medicine

摘　　要：目的:探讨膝周痛点射频热凝治疗顽固性膝关节骨性关节炎(knee osteoarthritis,KOA)疼痛的临床疗效观察。方法:60例顽固性膝关节骨性关节炎疼痛的病人,按随机数字表分为两组:观察组:膝周痛点射频热凝组(R组),行膝周痛点射频热凝加关节腔内玻璃酸钠注射;对照组:神经阻滞组(C组),行膝周神经痛点神经阻滞加关节腔内玻璃酸钠注射。分别于治疗前、治疗后1周、治疗后6周、治疗后3月和治疗后6月,记录骨关节炎指数、视觉模拟评分(visual analogue scale,VAS)、僵硬、功能障碍评分,(western ontario and mc Master universities osteoarthritis index,WOMAC)和不良反应。结果:两组病人术后1周骨关节炎指数均降低,6周及以后R组骨关节炎指数显著低于C组(P<0.01)。两组病人均未发生明显的不良反应。结论:膝周痛点射频热凝治疗膝关节骨性关节炎疗效较好,比神经阻滞治疗效果更持久,可成为治疗顽固性膝关节骨性关节炎的有效手段。Objective： To investigate the treatment effects of genicular nerve radiofrequency ablation on the refractory knee osteoarthritis pain. Methods： Sixty patients with refractory knee osteoarthritic pain were randomly divided into two groups： treatment group （group R） and control group （group C）. Group R received genicular nerves radiofrequency ablation. Group C received nerve blocking. Visual analogue scale （VAS） and western ontario and mcMaster universities osteoarthritis index （WOMAC） questionnaire score were measured at before treatment, and 1 week, 6 weeks, 3 months and 6 months after treatment to evaluate the therapeutic effect and adverse effects. Results： Compared with the group C, knee pain decreased more significantly in group R at 1 week after treatment, and WOMAC increased significantly in group R after treatment. No serious adverse effect appeared in this study. Conclusion： Genicular nerve radiofrequency ablation can reduce the pain and improve the function of the knee greatly. It might be a promising method for elderly knee osteoarthritis pain.

关 键 词：膝关节 骨性关节炎 疼痛 射频热凝 

分 类 号：R684.3[医药卫生—骨科学]