罗哌卡因切口浸润用于开腹肝脏切除术后镇痛作用观察  

Ropivacaine Infiltration Analgesia in Patients Post Hepatectomy

作　　者：冯伟[1] 蔡小丹 汪启乐 马垚[1] 林斌[1] 

机构地区：[1]徐州医学院附属宿迁医院南京鼓楼医院集团宿迁市人民医院,宿迁223800 [2]江苏省宿迁市第一人民医院,223899

出　　处：《中国实用医刊》2017年第13期72-74,共3页Chinese Journal of Practical Medicine

摘　　要：目的 探讨罗哌卡因术后切口局部浸润联合阿片类药物自控静脉镇痛用于开腹肝脏术后镇痛的临床可行性.方法 选择ASAⅠ~Ⅱ级、年龄30~60岁、择期全身麻醉下行肝脏手术患者36例,随机分为两组,A组行PCIA＋氯化钠注射液局部切口局部浸润镇痛,B组行PCIA＋罗哌卡因切口局部浸润镇痛,比较两组术后4 h、8 h、12 h、24 h的镇痛、镇静、呕吐评分及不良反应发生率.结果 B组术后8 h VAS评分明显低于A组（P〈 0.05）,术后嗜睡、呕吐发生率较低.结论 切口注射罗哌卡因可以缓解早期肝脏手术术后切口疼痛,降低术后镇静、呕吐的发生率,安全可行.Objective To evaluate the safety and efficiency in pain control for the cutting of intercostal nerve transection and peritoneal stretch stimulus longer postoperative incision after hepatectomy using ropivacaine hydrochloride for intra incisional infiltration.Methods Thirty-six patients of ASA class I-Ⅱ, age 30-60 years old ready for selective hepatectomy under general anesthesia were randomly divided into two groups.Group A：physiological saline 10 ml was given to each incision with PCIA after hepatectomy.Group B： roprivaciane hydrochloric 10 ml was given to each incision with PCIA after hepatectomy.All patients experienced general anesthesia with fentanyl-propofol and endotracheal intubation with mechanical ventilation.VAS score and Ramsay score were evaluated at 4, 8, 12, 24 hours after the operation.Results The scores of VSA in groupB was lower than that of group A at 8 h after surgery（P〈 0.05）.The incidence of drowsiness in group B was lower than that in group A after the operation.Conclusions Ropivacaine has good analgesic effect on patients with hepatectomy to reduce postoperative pain,and it is effective and safe.

关 键 词：罗哌卡因 浸润麻醉 肝切除 镇痛 

分 类 号：R614[医药卫生—麻醉学]