Dysgerminoma and Gonadoblastoma with Para-aortic Lymph Node Metastasis in a Patient with Swyer Syndrome  

作　　者：Ying Yao Hao-Jie He Jin-Song Han Hong-Yan Guo 

机构地区：[1]Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China

出　　处：《Chinese Medical Journal》2017年第15期1882-1883,共2页中华医学杂志（英文版）

摘　　要：To the Editor：In June 2013,a 17-year-old patient was admitted to our hospital for a pelvic mass and primary amenorrhea.The patient＇s cousin had a similar clinical presentation without a definite diagnosis.Physical examination revealed a phenotypic female with a slender body,poor mammary gland development,an infantile vulva,no pubic hair,and a normal-appearing vaginal orifice and vestibule.A hard and solid abdominal mass,approximately 12 cm in diameter,was found.The vagina was approximately 3.0 cm in length with a blind end measured by cotton swabs.The human chorionic gonadotropin （HCG） （40.64 mU/ml） and lactate dehydrogenase （LDH） （431 U/ml） levels were elevated.The follicle-stimulating hormone （111 mU/ml） and leutinizing hormone （27.8 mU/ml） levels were also elevated,while the E2,T,and A levels were below the reference values.The diurnal cortisol and adrenocorticotropic hormone （ACTH） levels were normal.Chromosome karyotype analysis was then done and revealed a result of 46XY.Pelvic computed tomography scan revealed multiple masses posterior to the uterus and involving the retroperitoneal abdominal aorta to the level of the left renal veins.To the Editor：In June 2013,a 17-year-old patient was admitted to our hospital for a pelvic mass and primary amenorrhea.The patient＇s cousin had a similar clinical presentation without a definite diagnosis.Physical examination revealed a phenotypic female with a slender body,poor mammary gland development,an infantile vulva,no pubic hair,and a normal-appearing vaginal orifice and vestibule.A hard and solid abdominal mass,approximately 12 cm in diameter,was found.The vagina was approximately 3.0 cm in length with a blind end measured by cotton swabs.The human chorionic gonadotropin （HCG） （40.64 mU/ml） and lactate dehydrogenase （LDH） （431 U/ml） levels were elevated.The follicle-stimulating hormone （111 mU/ml） and leutinizing hormone （27.8 mU/ml） levels were also elevated,while the E2,T,and A levels were below the reference values.The diurnal cortisol and adrenocorticotropic hormone （ACTH） levels were normal.Chromosome karyotype analysis was then done and revealed a result of 46XY.Pelvic computed tomography scan revealed multiple masses posterior to the uterus and involving the retroperitoneal abdominal aorta to the level of the left renal veins.

分 类 号：Q95-33[生物学—动物学] S865.23[农业科学—野生动物驯养]