肌肉生长抑制素在动物生产中的应用  

Myostatin Application in Animal Production

作　　者：赵义龙[1] 黄金凤 张琪智 买尔外提·波拉提 赵金香[5] 矫继峰[5] Zhao Yilong Huang Jinfeng Zhang Qizhi Maierwaiti·Bolati Zhao Jinxiaug et al.(Xinjiang Agricultural Vocational and Technical College,Xinjiang Changji 831100 Changji Huamu Animal Clinic,Xinjiang Changji 831100 Economic Development Board of Hongshan Farm,the Thirteenth Division of Xinjiang Production and Construction Corps,Xinjiang Hami 839000 Secondary Vocational and Technical School of Xinjiang Taeheng Prefeeture,Xinjiang Tacheng 834700 Yingkou Institute of Technology, Liaoning Yingkou 115014, China)

机构地区：[1]新疆农业职业技术学院动物科技学院,新疆昌吉831100 [2]新疆昌吉市华牧动物诊所.新疆昌吉831100 [3]新疆生产建设兵团第十三师红山农场经济发展局,新疆哈密839000 [4]塔城地区中等职业技术学校,新疆塔城834700 [5]营口理工学院,辽宁营口115014

出　　处：《四川畜牧兽医》2017年第8期29-31,共3页Sichuan Animal & Veterinary Sciences

基　　金：2017年度新疆农业职业技术学院资助项目(XJNZYKJ201718)

摘　　要：肌肉生长抑制素(MSTN)属于TGF-β超家族成员,是骨骼肌生长发育的负调节因子。MSTN作为胞外信号分子可与成肌细胞膜上的受体结合引起受体自身的磷酸化,启动细胞内一系列信号传导途径,作用于生肌决定因子(MyoD)靶基因的调控区,调节肌肉组成蛋白基因的表达,从而对骨骼肌的生长发育进行调控。Myostatin （MSTN） belongs to the members of the family of TGF-β, it is the negative regu- lation factors of skeletal muscle growth. MSTN as extracellular signal molecules can cause to receptors on the muscle cell membrane receptor phosphorylation, start a series of signal transduction in cells, act on the target gene regulation of decision factors （MyoD）, adjust the expression of muscle protein gene, thereby regulate and control the growth of skeletal muscle.

关 键 词：肌肉生长抑制素 生肌决定因子 调控 信号传导途径 

分 类 号：S852.2[农业科学—基础兽医学]